small fiber neuropathy

Full title: Small Fiber Polyneuropathy May Be a Nexus Between Autonomic Nervous System Dysregulation and Pain in Interstitial Cystitis/Bladder Pain Syndrome Abstract: Interstitial cystitis/bladder pain syndrome (IC/BPS) is a highly heterogeneous chronic and debilitating condition which...

Oldish paper but interesting. Abstract Small fiber neuropathy manifests in a variety of different diseases and often results in symptoms of burning pain, shooting pain, allodynia, and hyperesthesia. Diagnosis of small fiber neuropathy is determined primarily by the history and physical exam, but...

The pathophysiology of fibromyalgia syndrome (FMS) remains elusive, leading to a lack of objective diagnostic criteria and targeted treatment. We globally evaluated immune system changes in FMS by conducting multiparametric flow cytometry analyses of peripheral blood mononuclear cells and...

Background and Objective: Migraineurs often complain of orthostatic intolerance (OI), and its recognition is vital to appropriate treatment. This study attempts to identify and characterize autonomic dysfunction, comparing a sample of migraineurs with OI with a sample of migraineurs without...

Abstract Background/Aims: Long COVID is characterised by a range of potentially debilitating symptoms which develop in at least 10% of people who have recovered from acute SARS-CoV-2 infection. This study has quantified corneal sub-basal nerve plexus morphology and dendritic cell (DC) density...

" Brief Summary: Myalgic encephalomyelitis/Chronic fatigue syndrome (ME/CFS), otherwise known as Chronic fatigue syndrome (CFS) or myalgic encephalomyelitis (ME), is an under-recognized disorder whose cause is not yet understood. Suggested theories behind the pathophysiology of this condition...

Post COVID-19 syndrome associated with orthostatic cerebral hypoperfusion syndrome, small fiber neuropathy and benefit of immunotherapy: a case report https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502253/

Open access, https://www.tandfonline.com/doi/full/10.1080/24740527.2020.1712652

Paywall, https://www.sciencedirect.com/science/article/abs/pii/S1521661619306680 Not available via Sci hub at time of posting.

Review Neuroimmunology: What Role for Autoimmunity, Neuroinflammation, and Small Fiber Neuropathy in Fibromyalgia, Chronic Fatigue Syndrome, and Adverse Events after Human Papillomavirus Vaccination? https://www.mdpi.com/1422-0067/20/20/5164/htm

A review of small-fiber polyneuropathy. Interestingly, it says that evidence suggests it contributes to PEM. https://jamanetwork.com/journals/jamaneurology/article-abstract/2749401

Autonomic dysfunction and HPV immunization: an overview.

Paywalled at https://www.karger.com/Article/Abstract/493531#tab4

Have yet to watch it, but given Dr Systrom's SFNP findings, this may be interesting...

Dr. David M. Systrom of Brigham and Women’s Hospital (Boston) is confident that his team has objective evidence of small-fiber polyneuropathy (SFPN) in 40-50% of ME patients. Dr Systrom was interviewed by Llewelyn King in this video: . I put the timestamp at the part involved with SFPN but the...

Found this article this morning. Maybe some have heard of this dr. Talks more about treating pain but does mention CFS. I believe some here have been helped by IVIG...