stim1

ORAI Ca2+ channels and STIM1 drive capillary-to-arteriole communication in neurovascular coupling Neurovascular coupling (NVC), which is initiated by the brain’s dense capillary network, matches blood flow to neuronal activity. We found that ORAI1 channels and their regulator STIM1, the main...

Human coronavirus 3CL protease manipulates host protein STIM1 to facilitate immune evasion Coronaviruses rely on intricate interactions with host proteins to create an environment conducive to their replication and survival. The 3CL protease of coronavirus acts as a key mediator, serving a...

An emerging role for calcium signalling in innate and autoimmunity via the cGAS-STING axis Mathavarajah, Sabateeshan; Salsman, Jayme; Dellaire, Graham Abstract Type I interferons are effector cytokines essential for the regulation of the innate immunity. A key effector of the type I interferon...

https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2025.1637838/abstract Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a multisystemic disease characterized by exertional intolerance and fatigue which is often accompanied by muscleweakness and...

https://openresearch.surrey.ac.uk/esploro/outputs/doctoral/Characterising-the-Electrophysiological-Properties-of-Cells/99893266002346 Doctoral Thesis Characterising the Electrophysiological Properties of Cells in Health and Disease Krista Samantha Pauline Clarke University of Surrey Doctor of...