thrombosis

  1. Yann04

    [Preprint] Unravelling the Impact of SARS-CoV-2 on Hemostatic and Complement Systems: A Systems Immunology Perspective, 2024, Murad et al

    Abstract: The hemostatic system prevents and stops bleeding, maintaining circulatory integrity after injury. It directly interacts with the complement system, which is key to innate immunity. In coronavirus disease 2019 (COVID-19), dysregulation of the hemostatic and complement systems has been...
  2. Mij

    The Main protease (Mpro) from SARS-CoV-2 triggers plasma clotting in vitro by activating coagulation factors VII and FXII, 2024, Anna Pagotto et al

    Abstract Although the connection between COVID-19 and coagulopathy has been clear since the early days of SARS-CoV-2 pandemic, the underlying molecular mechanisms remain unclear. Available data support that the burst of cytokines and bradykinin, observed in some COVID-19 patients, sustains...
  3. SNT Gatchaman

    Thrombotic Consequences of COVID-19 Infection on Microsurgical Reconstruction, 2024, Han et al.

    Thrombotic Consequences of COVID-19 Infection on Microsurgical Reconstruction Sabrina H. Han; Kyle Ockerman; Matthew Kirchmier; Markos Mardourian; Jaimie Bryan; Elizabeth Cox; Harvey Chim; Lisa Spiguel; Arash Momeni; Sarah Sorice-Virk BACKGROUND Evidence has shown increased morbidity and...
  4. SNT Gatchaman

    Dysregulated Platelet Function in Patients with Post-Acute Sequelae of COVID-19, 2023, Aggarwal et al.

    Link to post with the abstract of the final published paper here Preprint Dysregulated Platelet Function in Patients with Post-Acute Sequelae of COVID-19 Anu Aggarwal; Tamanna K. Singh; Michael Pham; Matthew Godwin; Rui Chen; Thomas M. McIntyre; Alliefair Scalise; Mina K. Chung; Courtney...
  5. SNT Gatchaman

    A signature of platelet reactivity in CBC scattergrams reveals genetic predictors of thrombotic disease risk, 2023, Verdier et al.

    A signature of platelet reactivity in CBC scattergrams reveals genetic predictors of thrombotic disease risk Verdier, Hippolyte; Thomas, Patrick; Batista, Joana; Kempster, Carly; McKinney, Harriet; Gleadall, Nicholas; Danesh, John; Mumford, Andrew; Heemskerk, Johan W. M.; Ouwehand, Willem H...
  6. SNT Gatchaman

    Review Genomic communication via circulating extracellular vesicles and long-term health consequences of COVID-19, 2023, Nair et al.

    Genomic communication via circulating extracellular vesicles and long-term health consequences of COVID-19 Nair, Soumyalekshmi; Nova-Lamperti, Estefania; Labarca, Gonzalo; Kulasinghe, Arutha; Short, Kirsty R.; Carrión, Flavio; Salomon, Carlos COVID-19 continues to affect an unprecedented number...
    • SNT Gatchaman
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    • epigenetics extracellular vesicles gene expression glucose innate immune system lipid metabolism long covid metabolism sars-cov-2 spike protein thrombosis
    • Replies: 0
    • Forum: Long Covid research
  7. SNT Gatchaman

    Review Blood Coagulation and Beyond: Position Paper from the Fourth Maastricht Consensus Conference on Thrombosis, 2023, Akbulut et al.

    Blood Coagulation and Beyond: Position Paper from the Fourth Maastricht Consensus Conference on Thrombosis Asim Cengiz Akbulut; Ryanne A. Arisz; Constance C. F. M. J. Baaten; Gaukhar Baidildinova; Aarazo Barakzie; Rupert Bauersachs; Jur ten Berg; Wout W. A. van den Broek; H. C. de Boer; Amandine...
  8. SNT Gatchaman

    Monitoring circulating platelet activity to predict cancer-associated thrombosis, 2023, Li et al.

    Monitoring circulating platelet activity to predict cancer-associated thrombosis Li; Lu; Yang; Zhang; Wang; Chu; Wang; Qi; Anderson; Jiang; Song; Nie; Li A characteristic clinical complication in cancer patients is the frequent incidence of thrombotic events. Numerous studies have shown...
  9. SNT Gatchaman

    Plasma from patients with pulmonary embolism show aggregates that reduce after anticoagulation, 2023, Baker et al.

    Plasma from patients with pulmonary embolism show aggregates that reduce after anticoagulation Baker, Stephen R.; Halliday, Georgia; Ząbczyk, Michal; Alkarithi, Ghadir; Macrae, Fraser L.; Undas, Anetta; Hunt, Beverley J.; Ariëns, Robert A. S. Background Microclots, a term also used for amyloid...
  10. SNT Gatchaman

    SARS-CoV-2 spike protein induces lung endothelial cell dysfunction and thrombo-inflammation depending on the C3a/C3a receptor signalling, 2023 Perico+

    SARS-CoV-2 spike protein induces lung endothelial cell dysfunction and thrombo-inflammation depending on the C3a/C3a receptor signalling Perico, Luca; Morigi, Marina; Pezzotta, Anna; Locatelli, Monica; Imberti, Barbara; Corna, Daniela; Cerullo, Domenico; Benigni, Ariela; Remuzzi, Giuseppe The...
  11. SNT Gatchaman

    Prophylactic rivaroxaban in the early post-discharge period reduces the rates of hospitalization for AF and sudden cardiac death, 2023

    Prophylactic rivaroxaban in the early post-discharge period reduces the rates of hospitalization for atrial fibrillation and incidence of sudden cardiac death during long-term follow-up in hospitalized COVID-19 survivors Fiedler, Lukas; Motloch, Lukas J.; Dieplinger, Anna-Maria; Jirak, Peter...
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    • anticoagulation arrhythmia cardiac cardiovascular complications coagulation coagulopathy long covid sudden cardiac death thrombosis
    • Replies: 2
    • Forum: Long Covid research
  12. SNT Gatchaman

    Pulmonary circulation abnormalities in post-acute COVID-19 syndrome: dual-energy CT angiographic findings in 79 patients, 2023, Mohamed et al.

    Pulmonary circulation abnormalities in post-acute COVID-19 syndrome: dual-energy CT angiographic findings in 79 patients Mohamed, Islam; de Broucker, Virginie; Duhamel, Alain; Giordano, Jessica; Ego, Alice; Fonne, Nicolas; Chenivesse, Cécile; Remy, Jacques; Remy-Jardin, Martine Objectives To...
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    • dual energy ct hypercoagulability long covid lung disease lungs microcirculation microclots thrombosis
    • Replies: 2
    • Forum: Long Covid research
  13. SNT Gatchaman

    Analysis of thrombogenicity under flow reveals new insights into the prothrombotic state of patients with post-COVID syndrome, 2022

    Analysis of thrombogenicity under flow reveals new insights into the prothrombotic state of patients with post-COVID syndrome Adela Constantinescu-Bercu, Anna Kessler, Rens de Groot, Bertina Dragunaite, Melissa Heightman, Toby Hillman, Laura C. Price, Ewan Brennan, Raphael Sivera, Karen...
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    • Thread
    • adamts13 collagen long covid microclots microfluidics thrombosis von willebrand factor
    • Replies: 14
    • Forum: Long Covid research
  14. SNT Gatchaman

    SARS-CoV-2 Spike protein promotes vWF secretion and thrombosis via endothelial cytoskeleton-associated protein 4 (CKAP4), 2022, Li et al

    SARS-CoV-2 Spike protein promotes vWF secretion and thrombosis via endothelial cytoskeleton-associated protein 4 (CKAP4) Kan Li, Liu Yao, Jin Wang, Hao Song, Yan-hong Zhang, Xue Bai, Kai Zhang, Dong-ming Zhou, Ding Ai, Yi Zhu Letter to Nature: Signal Transduction and Targeted Therapy Link | PDF
  15. SNT Gatchaman

    COVID-19 patient fibrinogen produces dense clots with altered polymerization kinetics, ... increased sialic acid, 2022, Moiseiwitsch et al

    COVID-19 patient fibrinogen produces dense clots with altered polymerization kinetics, partially explained by increased sialic acid Moiseiwitsch N, Zwennes N, Szlam F, Sniecinski R, Brown A Background: Thrombogenicity is a known complication of COVID-19, resulting from SARS-Cov-2 infection...
  16. SNT Gatchaman

    Association of COVID-19 With Major Arterial & Venous Thrombotic Diseases: A Population-Wide Cohort Study of 48 million Adults in England & Wales, 2022

    Association of COVID-19 With Major Arterial and Venous Thrombotic Diseases: A Population-Wide Cohort Study of 48 Million Adults in England and Wales Knight R, Walker V, Ip S, Cooper JA, Bolton T, Keene S, Denholm R, Akbari A, Abbasizanjani H, Torabi F, Omigie E, Hollings S, North TL, Toms R...
  17. Andy

    Evidence of SARS-CoV-2 spike protein on retrieved thrombi from COVID-19 patients, 2022, De Michele et al

    Abstract The pathophysiology of COVID-19-associated coagulopathy is complex and not fully understood. SARS-CoV-2 spike protein (SP) may activate platelets and interact with fibrin(ogen). We aimed to investigate whether isolated SP can be present in clots retrieved in COVID-19 patients with...
  18. SNT Gatchaman

    Early antithrombotic post-discharge therapy using prophylactic DOAC or dipyridamole improves survival and cardiovascular outcomes in COVID-19 (2022)

    Early antithrombotic post-discharge therapy using prophylactic DOAC or dipyridamole improves long-term survival and cardiovascular outcomes in hospitalized COVID-19 survivors Motloch LJ, Jirak P, Mirna M, Fiedler L, Davtyan PA, Lakman IA, Gareeva DF, Tyurin AV, Gumerov RM, Matskeplishvili ST...
  19. SNT Gatchaman

    [Preprint] COVID-19 Neuropathology: evidence for SARS-CoV-2 invasion of Human Brainstem Nuclei, 2022, Emmi et al

    COVID-19 Neuropathology: evidence for SARS-CoV-2 invasion of Human Brainstem Nuclei Aron Emmi, Stefania Rizzo, Luisa Barzon, Michele Sandre, Elisa Carturan, Alessandro Sinigaglia, Silvia Riccetti, Mila della Barbera, Rafael Boscolo-Berto, Patrizia Cocco, Veronica Macchi, Angelo Antonini, Monica...
  20. SNT Gatchaman

    Premortem skin biopsy assessing microthrombi, IFN I antiviral & regulatory proteins and complement correlates with Covid19 clinical stage, 2022

    Premortem Skin Biopsy Assessing Microthrombi, Interferon I Antiviral and Regulatory Proteins, and Complement Deposition Correlates with Coronavirus Disease 2019 Clinical Stage Jeffrey Laurence, Gerard Nuovo, Sabrina E. Racine-Brzostek, Madhav Seshadri, Sonia Elhadad, A. Neil Crowson, J. Justin...
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