traumatic brain injury

Exercise-Induced Symptom Exacerbation and Adverse Events in Moderate-to-Severe Traumatic Brain Injury Gallow, Sara BPhysio; McGinley, Jennifer PhD; Olver, John MD, FAFRM; McKenzie, Dean PhD; Williams, Gavin PhD Objective To determine the incidence of exercise-induced symptom exacerbation and...

Abstract Objective: To examine the development of different dimensions of fatigue and subjective and objective measures of sleep in the first 18 months post moderate to severe traumatic brain injury (TBI), and explore the association with biological (processing speed), psychological (mood), and...

Neuroplastic changes in patients with functional seizures following neurobehavioral therapy Sharma; Allendorfer; Correia; Gaston; Goodman; Grayson; Philip; LaFrance; Szaflarski Given the high prevalence of functional neurological symptom disorder and its negative effects on the individual...

Post-Concussion Brain Changes Relative to Pre-Injury White Matter and Cerebral Blood Flow Nathan W. Churchill, Michael G. Hutchison, Simon J. Graham, Tom A. Schweizer BACKGROUND AND OBJECTIVES Medical clearance for return to play (RTP) after sports-related concussion is based on clinical...

https://pubmed.ncbi.nlm.nih.gov/39921702/ Abstract Chronic traumatic encephalopathy (CTE), a neurodegenerative disease associated with repetitive head injuries, is characterised by perivascular hyperphosphorylated tau (p-tau) accumulations within the depths of cortical sulci. Although the...

Repetitive Low-Level Blast Exposure Alters Circulating Myeloperoxidase, Matrix Metalloproteinases, and Neurovascular Endothelial Molecules in Experienced Military Breachers Rhind, Shawn G.; Shiu, Maria Y.; Tenn, Catherine; Nakashima, Ann; Jetly, Rakesh; Sajja, Venkata Siva Sai Sujith; Long...

Background: Traumatic brain injury (TBI) disrupts normal brain tissue and functions, leading to high mortality and disability. Severe TBI (sTBI) causes prolonged cognitive, functional, and multi-organ dysfunction. Dysfunction of the autonomic nervous system (ANS) after sTBI can induce...

Poor long-term outcomes and abnormal neurodegeneration biomarkers after military traumatic brain injury: the ADVANCE study Neil SN Graham; Grace Blissitt; Karl Zimmerman; Lydia Orton; Daniel Friedland; Emma Coady; Rhiannon Laban; Elena Veleva; Amanda J Heslegrave; Henrik Zetterberg; Susie...

Full title: One-year follow-up of neurobehavioral therapy in functional seizures or epilepsy with traumatic brain injury: A nonrandomized controlled trial Abstract Objective Patients with traumatic brain injury (TBI) often present with seizures (functional and/or epileptic), but treatments for...

Plasma biomarkers in chronic single moderate–severe traumatic brain injury Gershon Spitz, Amelia J. Hicks, Stuart J. McDonald, Vincent Dore, Natasha Krishnadas, Terence J. O’Brien, William T O’Brien, Lucy Vivash, Meng Law, Jennie L. Ponsford, Christopher Rowe, Sandy R. Shultz Abstract Blood...

Diffusion tensor analysis of white matter tracts is prognostic of persisting post-concussion symptoms in collegiate athletes Bertò; Rooks; Broglio; McAllister; McCrea; Pasquina; Giza; Brooks; Mihalik; Guskiewicz; Goldman; Duma; Rowson; Port; Pestilli BACKGROUND AND OBJECTIVES After a concussion...

Experts discover trigger for deadly motor neurone disease (msn.com)

Aquaporins: Gatekeepers of Fluid Dynamics in Traumatic Brain Injury Czyżewski, Wojciech; Litak, Jakub; Sobstyl, Jan; Mandat, Tomasz; Torres, Kamil; Staśkiewicz, Grzegorz Aquaporins (AQPs), particularly AQP4, play a crucial role in regulating fluid dynamics in the brain, impacting the...

Full Title: Noradrenaline-induced change in cerebral blood flow in health, traumatic brain injury and critical illness: a systematic review with meta-analysis, 2024, Lingzhong Meng et al Summary Background Noradrenaline is a standard treatment for hypotension in acute care. The precise effects...

Abstract Background Traumatic brain injury (TBI) causes significant blood-brain barrier (BBB) breakdown, resulting in the extravasation of blood proteins into the brain. The impact of blood proteins, especially fibrinogen, on inflammation and neurodegeneration post-TBI is not fully understood...

A Comprehensive and Broad Approach to Resting-State Functional Connectivity in Adult Patients with Mild Traumatic Brain Injury Soroush Arabshahi; Sohae Chung; Alaleh Alivar; Prin X. Amorapanth; Steven R. Flanagan; Farng-Yang A. Foo; Andrew F. Laine; Yvonne W. Lui BACKGROUND AND PURPOSE Several...

Effects of Low-Level Blast on Neurovascular Health and Cerebral Blood Flow: Current Findings and Future Opportunities in Neuroimaging Kilgore, Madison O.; Hubbard, W. Brad Low-level blast (LLB) exposure can lead to alterations in neurological health, cerebral vasculature, and cerebral blood...

Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia Raquel Garza; Yogita Sharma; Diahann A.M. Atacho; Arun Thiruvalluvan; Sami Abu Hamdeh; Marie E. Jönsson; Vivien Horvath; Anita Adami; Martin Ingelsson; Patric Jern; Molly...

Full title: Persistent Neurological, Dissociative, and Amnestic Symptoms Following a Mild Traumatic Brain Injury in an Adolescent: A Complex Case of Conversion Disorder Abstract The diagnosis of conversion disorder may be given to patients with unexplained neurological symptoms after the...

Introduction Self-reported memory difficulties (forgetting familiar names, misplacing objects) often persist long after a mild traumatic brain injury (mTBI), despite normal neuropsychological test performance. This clinical presentation may be a manifestation of a functional cognitive disorder...