This is a thread to discuss the evidence on obstructive sleep-disordered breathing and orthostatic intolerance.
Sleep-disordered Breathing and Hypotension, 2001, Guilleminault et al.
In a series of 4,409 consecutive Stanford sleep clinic referrals, low resting blood pressure (<105/65 here) was...
Obstructive Sleep Apnea and Orthostatic Hypotension: An Unconventional Association
Ryan S Cobb , Mildred Barnett , Kevin Patel
https://academic.oup.com/sleep/article/48/Supplement_1/A618/8135020 (PDF available)
Introduction
Although Obstructive Sleep Apnea (OSA) has a commonly recognized...
Exploring the Abnormal Modulation of the Autonomic Systems during Nasal Flow Limitation in Upper Airway Resistance Syndrome by Hilbert–Huang Transform
Chen Lin, Men-Tzung Lo, Christian Guilleminault
https://pmc.ncbi.nlm.nih.gov/articles/PMC5625011/ (PDF available)
Patients with nasal flow...
The cyclic alternating pattern demonstrates increased sleep instability and correlates with fatigue and sleepiness in adults with upper airway resistance syndrome
Christian Guilleminault, M Cecilia Lopes, Chad C Hagen, Agostinho da Rosa...
The effects of nasal anesthesia on breathing during sleep
D P White, R J Cadieux, R M Lombard, E O Bixler, A Kales, C W Zwillich
https://pubmed.ncbi.nlm.nih.gov/4062052/
Sci-Hub link: https://sci-hub.st/10.1164/arrd.1985.132.5.972
Inability to breathe through the nose is an increasingly...
The symptoms and signs of upper airway resistance syndrome: a link to the functional somatic syndromes
Avram R Gold, Francis Dipalo, Morris S Gold, Daniel O'Hearn...
This is a thread to discuss the evidence pertaining to obstructive sleep-disordered breathing - upper airway resistance syndrome/obstructive sleep apnea syndrome (UARS/OSAS) - and chronic insomnia. Many people with ME/CFS and related disorders like fibromyalgia experience chronic insomnia...
Chronic insomnia remitting after maxillomandibular advancement for mild obstructive sleep apnea: a case series
Michael Proothi, Victor J R Grazina, Avram R Gold
https://pmc.ncbi.nlm.nih.gov/articles/PMC6693215/ (PDF available)
Background: Chronic insomnia and obstructive sleep apnea are both...
Prospective Assessment of Nocturnal Awakenings in a Case Series of Treatment-Seeking Chronic Insomnia Patients: A Pilot Study of Subjective and Objective Causes
Barry Krakow, Edward Romero, Victor A Ulibarri, Shara Kikta
https://pmc.ncbi.nlm.nih.gov/articles/PMC3490361/ (PDF available)...
A comparison of inspiratory airflow dynamics during sleep between upper airway resistance syndrome patients and healthy controls
Avram R. Gold, Joan E. Broderick, Morris S. Gold & Mohammad M. Amin...
Objective versus subjective excessive daytime sleepiness in OSA: Quantifying the impact of fatigue
Morris S Gold, Riccardo A Stoohs, Avram R Gold
https://www.sciencedirect.com/science/article/abs/pii/S1389945726001061
Background
In patients with obstructive sleep apnea (OSA), excessive daytime...
Somatic arousal and sleepiness/fatigue among patients with sleep-disordered breathing
Morris S. Gold, Tshering Amdo, Nadia Hasaneen and Avram R. Gold
https://www.researchgate.net/publication/289535169_Somatic_arousal_and_sleepinessfatigue_among_patients_with_sleep-disordered_breathing
Sci-Hub...
ETA: Updated/edited AI summary of the theory with links to S4ME threads for most of the relevant studies.
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