Jonathan Edwards
Senior Member (Voting Rights)
It would target the NK cells just the same. The absence of many NK cells from blood doesn't necessarily mean there aren't any. They may be busy in tissues.
Preprint A Proposed Mechanism for ME/CFS Invoking Macrophage Fc-gamma-RI and Interferon Gamma, 2025, Edwards, Cambridge and Cliff
- Thread starter Nightsong
- Start date
It would target the NK cells just the same. The absence of many NK cells from blood doesn't necessarily mean there aren't any. They may be busy in tissues.
hotblack
Senior Member (Voting Rights)
Ah, so they’d still be the key strut but less visible. Interesting.
I suppose I was thinking maybe there are various routes of, say, interferon stimulation. And maybe the sum of all those is the problem. So depending upon which dial you have most ready access to, or which is most significant for a patient, you could turn that one down and let the rest of the system sort itself out. So maybe for some it was NK cells, but maybe for others some other inhibitor or strut would be better to knock out.