Abnormal Glutamatergic and Serotonergic Connectivity in Visual Snow Syndrome and Migraine with Aura

Hoopoe

Senior Member (Voting Rights)
Our results show that glutamate and serotonin are involved in brain connectivity alterations in areas of the visual, salience, and limbic systems in VSS. Importantly, altered serotonergic connectivity is independent of migraine in VSS, and simultaneously comparable to that of migraine with aura, highlighting a shared biology between the disorders.

https://onlinelibrary.wiley.com/doi/full/10.1002/ana.26745
 
I'd never heard of Visual Snow Syndrome before. Once between the ages of 5 and 7 I experienced what I described as 'cotton wool' across my field of vision, and I was terrified and had to sleep in the bed of my aunt and uncle for the rest of the night. I am pretty sure I was OK in the morning. I recall struggling to find my way around. It sounds like it could have been VSS.

I had recently suffered bad chickenpox followed by Bell's Palsy which did not fully recover. I had also had to move out of my family home due to my mother being terminally ill.
 
I developed VSS in December 24 after barely sleeping for a month. Has not gone away after my sleep improved. The opthalmologist didn’t find anything, I might be heading for some neurological exams if my health allows it.
 
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