Anyone tried H2O2 therapy?

oroffey said:
Good feedback. Thank you.

I totally understand the need for a scientific approach to this. I’m just concerned that this is shunned due to the perception of “bleach” (related media to that) and that there hasn’t been any research papers in to whether it is efficacious. USA Today study only says “no research to support the claim” - which I agree with but why is that research not being done?

This means the only “evidence” out there is the blogs online but there seem to be more and more people saying it works for them (the one I posted was just one example).

Interestingly while writing this I found this journal article (not looked at peer review) but something at least:https://www.frontiersin.org/articles/10.3389/fneur.2022.841310/full

“Guan et al. (37) examined the effects of a H2/O2mixed gas (67% H2, 33% O2) on patients with COVID-19 by an open-label multicenter clinical trial and showed that the improvements in disease severity, dyspnea, cough, chest distress, chest pain, and oxygen saturation were significantly greater in H2/O2 treatment group (44 patients) than those in control group (46 patients)”

Seems to indicate that there could be something in this? However perhaps in H2/O2 form instead.
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But it is what bleach is?

This is what is used to bleach hair. It can bleach teeth. It will bleach clothes if it drops on them etc. It smells of bleach even when it is a very weak solution in a mouthwash

As there are warnings for example about using too much too often even as a mouthwash then I suspect that might be a good place to look for research as there are likely connections there with regards to the harm done / links to issues?
 
H2O2 is not a bleach. SOD(Superoxide dismutase) catalyzes the dismutation of superoxide anion to hydrogen peroxide on every living organism's cell including microbes, which some of them are resistant to it since do not possesses CAT(catalyze) enzyme. I think I will create proper post in near future of why H2O2 might be an answer, since 100% of patients I was witnessed it was administrated to reacted flawlessly to it, removing all symptoms within few days. The problem is the form of delivery of this powerful compound.
 
H2O2 is a bleaching agent, as anyone with peroxide blonde hair knows.
It is not bleach if that term is being used to mean chlorine containing oxidising agents like hypochlorite but it is a bleach in the sense that it bleaches. The term bleach is also appropriate since H2O2 kills both bacteria and human cells in sufficient concentration. The rate of generation of H2O2 from superoxide in human tissues is presumably well below that level. The problem with recommending H2O2 as a therapy is that it is highly toxic at concentrations that can be bought and people who are foolish enough to use it at all may well be foolish enough to use it at the wrong dose.

There is not a scrap of evidence for it being of any value in ME/CFS. Any more than there is a scrap of evidence for UFOs despite people saying that they know lots of people who have seen them and who have seen bits of aliens in jars.

You can fool some of the people all of the time...
 
Wikipedia said:
Hydrogen peroxide is a chemical compound with the formula H₂O₂. In its pure form, it is a very pale blue liquid that is slightly more viscous than water. It is used as an oxidizer, bleaching agent, and antiseptic, usually as a dilute solution in water for consumer use and in higher concentrations for industrial use.
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Wikipedia said:
Bleach is the generic name for any chemical product that is used industrially or domestically to remove colour from fabric or fiber or to disinfect after cleaning. It often refers specifically to a dilute solution of sodium hypochlorite, also called "liquid bleach".
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H2O2 isn't the chemical we buy in the supermarket in a bottle labelled 'Bleach'. But H2O2 bleaches. It is therefore 'a bleach'.
 
Jonathan Edwards said:
There is not a scrap of evidence for it being of any value in ME/CFS.
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True, cause nobody tried or make a single effort to finally take a look of approaches like this human study(link below). What if only hermitic approach is an only approach to solve oxidative stress related illnesses? What then? Will we be waiting for "safe" treatment forever? Look like it...

“The use of intravenous ascorbic acid and hydrogen peroxide resulted in a statistically significant reduction of pain in patients with moderate to severe pain from the Chikungunya virus immediately after treatment.”

https://www.researchgate.net/profil...ith-chikungunya.pdf?origin=publication_detail
 
Ildias said:
“The use of intravenous ascorbic acid and hydrogen peroxide resulted in a statistically significant reduction of pain in patients with moderate to severe pain from the Chikungunya virus immediately after treatment.”
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Well now. Ascorbic acid is a reducing agent. They gave 25-50gm. I only read the abstract but this seems to have been mixed with 3ml of 3% H2O2, which would be 90mg. The molecular weight of ascorbate is 176, of H2O2 34. Assuming that one ascorbate can reduce one H2O2 I work that out at there being about 50-100 times as much ascorbate as needed to completely reduce the H2O2 to water. So it seems a pretty dumb thing to do even if you think H2O2 is useful.

And there seem to be no controls and the outcome measure is subjective so this could easily win the prize for the very worst trials ever done.
 
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