The opioid crisis and growing awareness of the dangers of addiction to pain medication are prompting renewed calls for the use of pill placebos in place of active treatments, backed by familiar claims about the magical powers of the placebo.
Witness the press release for a recent study in the prestigious Nature Communications: “
Sugar pills relieve pain for chronic pain patients“.
Here are some excerpts:
“Their brain is already tuned to respond,” said senior study author A. Vania Apkarian, professor of physiology at Northwestern University Feinberg School of Medicine. “They have the appropriate psychology and biology that puts them in a cognitive state that as soon as you say, ‘this may make your pain better,’ their pain gets better.”
There’s no need to fool the patient, Apkarian said.
“You can tell them, ‘I’m giving you a drug that has no physiological effect but your brain will respond to it,'” he said. “You don’t need to hide it. There is a biology behind the placebo response.”
And:
The individuals whose pain decreased as a result of the sugar pill had a similar brain anatomy and psychological traits. The right side of their emotional brain was larger than the left, and they had a larger cortical sensory area than people who were not responsive to the placebo. The chronic pain placebo responders also were emotionally self-aware, sensitive to painful situations and mindful of their environment.
