Blood test for autism claims 90% accuracy

Marco · Feb 19, 2018

Not much I can add to the article except to note that the findings suggest a metabolic aetiology :

“Our finding is consistent with low-level inflammation in ASD and also with disturbance in the supply of amino acids to neurons—the latter has also been suggested in previous gene association studies,” Rabbini said.
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https://gizmodo.com/researchers-say-theyve-created-a-90-accurate-blood-tes-1823087752

Marco · Feb 19, 2018

Just for a little balance others have expressed some scepticism :

Potential blood and urine test for autism greeted with skepticism

https://newatlas.com/autism-blood-urine-test-biomarkers/53457/

Marco · Feb 19, 2018

Here's the paper :

Advanced glycation endproducts, dityrosine and arginine transporter dysfunction in autism - a source of biomarkers for clinical diagnosis

https://molecularautism.biomedcentral.com/articles/10.1186/s13229-017-0183-3

arewenearlythereyet · Feb 19, 2018

Seems interesting, but I think on balance I will remain skeptical until the rest of the work is done on a larger sample size etc.

Indigophoton · Jun 19, 2018

The follow-up study has been published:

One year after researchers published their work on a physiological test for autism, a follow-up study confirms its exceptional success in assessing whether a child is on the autism spectrum. A physiological test that supports a clinician’s diagnostic process has the potential to lower the age at which children are diagnosed, leading to earlier treatment. Results of the study, which uses an algorithm to predict if a child has autism spectrum disorder (ASD) based on metabolites in a blood sample, published online today, appear in the June edition of Bioengineering & Translational Medicine.

“We looked at groups of children with ASD independent from our previous study and had similar success. We are able to predict with 88 percent accuracy whether children have autism,” said Juergen Hahn, lead author, systems biologist, professor, head of the Rensselaer Polytechnic Institute Department of Biomedical Engineering, and member of the Rensselaer Center for Biotechnology and Interdisciplinary Studies (CBIS). “This is extremely promising.”
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https://neurosciencenews.com/autism-blood-test-9379

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Blood test for autism claims 90% accuracy

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