CoQ10 - Coenzyme Q10

[forestglip]

I found a manuscript. Not published per say.

https://cdn.clinicaltrials.gov/large-docs/60/NCT02865460/Prot_SAP_000.pdf

Thanks. It looks like the protocol, not results, though.

 

[Sly Saint]

Experts review the evidence on coenzyme Q10 and cognitive decline

In a recent study published in the journal Nutrients, Australian researchers reviewed the effects of coenzyme Q10 (CoQ10) supplementation on cognition. Approximately 22% of the world’s population is estimated to be 60 years or older by 2050. Accompanying this change will be an increase in people with cognitive decline and the prevalence of neurodegenerative diseases. The causes of neurodegenerative diseases and cognitive decline are multifactorial, but the major contributors are oxidative stress, inflammation, poor cardiovascular health, decreased cerebral blood flow, and mitochondrial dysfunction. These multiple processes in the body and brain require various targeted therapeutic approaches. Various approaches to addressing age-related cognitive decline have been employed, including dietary modifications, physical activity, medications, and nutritional supplements. CoQ10 is an antioxidant and metabolic stimulant that positively influences biological mechanisms relevant to cognition, with mixed effects on cognitive test performance in trials. In the present study, researchers reviewed the effects of CoQ10 supplementation on cognition.

Experts review the evidence on coenzyme Q10 and cognitive decline

Researchers reviewed evidence on coenzyme Q10 (CoQ10) and cognition, finding strong biological support and positive results in animal models but mixed outcomes in human trials. Larger, high-quality studies are needed to clarify whether CoQ10 can protect against cognitive decline and...

www.news-medical.net

 

[DHagen]

Experts review the evidence on coenzyme Q10 and cognitive decline

Researchers reviewed evidence on coenzyme Q10 (CoQ10) and cognition, finding strong biological support and positive results in animal models but mixed outcomes in human trials. Larger, high-quality studies are needed to clarify whether CoQ10 can protect against cognitive decline and...

www.news-medical.net

"The other trial found no significant differences in the digit symbol substitution test, the trail making test, and the memory performance index (MPI) in people taking ubiquinol (reduced form of CoQ10). Notably, people who were cognitively normal at baseline showed significant improvements in MPI following 34 weeks of ubiquinol supplementation."​

I hate how much of my limited brain power I end up wasting trying to follow what appear to be directly contradictory statements in publications (both popular and research-focused) and in attempting to determine whether I am simply too stupid to understand what is being said, or whether editorial standards have really fallen so far.