Trial By Error: Time to Retract the LP Study; Letter to Archives of Disease in Childhood
http://www.virology.ws/2019/06/03/t...y-letter-to-archives-of-disease-in-childhood/
3 June 2019
By David Tuller, DrPH
Let me say this directly: It is way past time for Archives of Disease in Childhood to consign the pediatric Lightning Process study to the trash bin.
As I have pointed out repeatedly, the Bristol University investigators recruited more than half their participants before trial registration, swapped outcome measures based on the early results, and then failed to disclose these critical details in the paper. More than a decade ago, all the major medical journals banned the publication of any studies in which recruitment pre-dates trial registration. For that reason alone, Archives of Disease in Childhood, a BMJ journal, should not have published it in the first place...
http://www.virology.ws/2019/06/03/t...y-letter-to-archives-of-disease-in-childhood/
3 June 2019
By David Tuller, DrPH
Let me say this directly: It is way past time for Archives of Disease in Childhood to consign the pediatric Lightning Process study to the trash bin.
As I have pointed out repeatedly, the Bristol University investigators recruited more than half their participants before trial registration, swapped outcome measures based on the early results, and then failed to disclose these critical details in the paper. More than a decade ago, all the major medical journals banned the publication of any studies in which recruitment pre-dates trial registration. For that reason alone, Archives of Disease in Childhood, a BMJ journal, should not have published it in the first place...
