Did the David Nutt SAFFE Xyrem drug sleep study ever publish?

This study was funded 2012, started 2013 but I don't remember seeing a final paper published within th results, does anyone? Thank you.

https://www.hra.nhs.uk/planning-and...unctioning-in-chronic-fatigue-syndrome-saffe/

 

The study I heard about was for fibro patients. I don't know what happened to it, but I think it showed very good results. My sleep doctor had been very hopeful the FDA would approve the use of Xyrem for fibro after the favorable study, but they declined, infuriating my doctor.

I used to have narcolepsy, but recovered from it. I took Xyrem for a number of years and thankfully insurance did pay for it. My copay was usually $40 a month. The out-of-pocket costs would have been astronomical, in the thousands a month. A greed-head company has the patent until 2020, I believe. Talk about the ugly side of American capitalism.

 

Sorry, I just realized you were talking about a UK study. My mind just went to the American study.

 

Xyrem is GHB, right? That stuff sends me to sleep alright! Now only if they'd licence it for us...

 

What about doses and prices?

 

I think it's relatively hard to get hold of. I've not tried purchasing it myself.

 

if I remember correctly that was a drug of choice for many gay people in the 80,s and more mainstream recreational drug in the 90.s .from my limited knowledge it cause significant cognitive difficulties severe memory loss .can also lead to psychotic episodes. I would not risk all that for an occasional good nights sleep.

 

It still is. I think the negative side-effects are rather overstated, however. Such is the case with most recreational drugs--and such responses are more politically and socially driven than scientific.

It's also likely street GHB is mixed with other things or replaced with other substances entirely, so we shouldn't base our assumptions purely on anecdotes of street use.

Given that ketamine and MDMA are showing promise, and the former always struck me as far more psychoactive than GHB, I suspect it may have uses that should be explored further--if only we could get past our attitudes to recreational drugs in the first place.

 

I don't remember seeing such a study published.