sleep

Wearable-derived Sleep Measurements are Associated with Long-COVID in the RECOVER Adult Cohort Abstract Wearables yield a wide array of sleep-related measures that are relevant to Long COVID. We leveraged wearables-derived sleep measures (WDSM) to identify differences between individuals with...

Neocortical long-range inhibition promotes cortical synchrony and sleep Abstract Sleep and wakefulness are associated with distinct cortical patterns of rhythmic activiy. During low-arousal states such as slow-wave sleep, synchronous low-frequency rhythms dominate activity across widespread...

Bidirectional Associations Between Autonomic Function, Sleep Quality, and Daily Fatigue and Energy Symptoms in Long COVID: Longitudinal Digital Health Study Nana Yaw Aboagye; Mark R Baker; Kenneth Baker; Silvia Del Din BACKGROUND Long COVID is characterized by persistent fatigue, with disrupted...

Chronic fatigue, unrefreshing sleep and nocturnal polysomnography Christian Guilleminault, Dalva Poyares, Agostinho da Rosa, Ceyda Kirisoglu, Tatiana Almeida, Maria Cecilia Lopes https://www.sciencedirect.com/science/article/abs/pii/S1389945706001079 Sci-Hub...

Genetic architecture of sleep in a genome wide association study of device measured sleep traits Abstract Abstract Sleep is essential for health and regulated by genetic and environmental factors. We perform genome-wide association studies of device-measured sleep duration, efficiency, and...

Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways Insomnia is the second most prevalent mental disorder, with no sufficient treatment available. Despite substantial heritability, insight into the associated genes and neurobiological...

Chronic widespread musculoskeletal pain, fatigue, depression and disordered sleep in chronic post-SARS syndrome; a case-controlled study Harvey Moldofsky, John Patcai https://pmc.ncbi.nlm.nih.gov/articles/PMC3071317/ (PDF available) Background: The long term adverse effects of Severe Acute...

Highlights The predominant changes observed in athletes' sleep are a decrease in sleep efficiency accompanied by an increase in sleep fragmentation. Even though objective modifications occurred, only minimal subjective changes were observed postrace in endurance athletes. Objective sleep...

Microglia regulate sleep and thermoregulatory stability Sleep fragmentation disrupts physiological homeostasis, including thermoregulation, metabolism, and immune signaling; however, cellular mechanisms that stabilize core body temperature and sleep architecture during disrupted sleep remain...

Persistent Sleep Disturbance Following Pandemic Lockdowns: Longitudinal Findings From the UK COVID ‐19 Symptom Study Biobank ABSTRACT Sleep disturbance and fatigue were highly prevalent during the COVID-19 pandemic, in both infected and non-infected individuals, though mostly assessed...

Systems neuroendocrinology in ME/CFS and long COVID: a chronobiological framework for hormone-based research Hormonal dysregulation is increasingly reported in ME/CFS and Long COVID, yet the broader role of neuroendocrine disruption in these conditions remains underexplored. While changes in...

Wake-active brainstem GABA neurons signal sleep pressure by upregulating AMPA receptors to drive recovery sleep How the brain compensates for sleep deprivation (SD) by generating recovery sleep (RS) is not understood. Using Ca²⁺ photometry, we identified a WAKE/rapid eye movement sleep...

Has anyone had a recent(ish) at-home sleep study, either on the NHS or arranged privately? If on the NHS, I am wondering if this is something that usually requires a referral to a sleep clinic or hospital consultant, or whether this can be organised and completed in primary care? If private...

Sleep in myalgic encephalomyelitis/chronic fatigue syndrome shows marked night-to-night fluctuation under free-living conditions—results from a matched case-control study PURPOSE Unrefreshing and non-restorative sleep is a hallmark complaint in people with myalgic encephalomyelitis/chronic...

Somatic syndromes, insomnia, anxiety, and stress among sleep disordered breathing patients Tshering Amdo, Nadia Hasaneen, Morris S Gold, Avram R Gold https://www.researchgate.net/publication/291418836_Somatic_syndromes_insomnia_anxiety_and_stress_among_sleep_disordered_breathing_patients (PDF)...

Facility-Measured Sleep Electroencephalographic Microstructures in Long COVID STUDY OBJECTIVES Sleep electroencephalographic (EEG) microstructures are related to brain functions, providing a window into the unrefreshing, non-restorative sleep and daytime fatigue symptoms in long COVID (LC) and...

Association of Obstructive Sleep Apnea with Post-Acute Sequelae of SARS-CoV-2 infection https://pmc.ncbi.nlm.nih.gov/articles/PMC11144080/ (PDF available) Background: Obstructive sleep apnea is associated with COVID-19 infection. Less clear is whether obstructive sleep apnea is a risk factor...

The relationship between nonrestorative sleep and persistent post-acute sequelae of COVID-19: a longitudinal study of recovery trajectories Nonrestorative sleep (NRS) may contribute to the persistence of post-acute sequelae of COVID-19 (PASC), but no longitudinal studies have investigated this...

Obstructive Sleep Apnea and Orthostatic Hypotension: An Unconventional Association Ryan S Cobb , Mildred Barnett , Kevin Patel https://academic.oup.com/sleep/article/48/Supplement_1/A618/8135020 (PDF available) Introduction Although Obstructive Sleep Apnea (OSA) has a commonly recognized...

Exploring the Abnormal Modulation of the Autonomic Systems during Nasal Flow Limitation in Upper Airway Resistance Syndrome by Hilbert–Huang Transform Chen Lin, Men-Tzung Lo, Christian Guilleminault https://pmc.ncbi.nlm.nih.gov/articles/PMC5625011/ (PDF available) Patients with nasal flow...