Editorial: Infectious and inflammatory mechanistic underpinnings of CFS/ME (2023) Burton

[Milo]

There is no abstract but it is open access and quick read. Here is an excerpt:

Recent reanalysis of the DIOS (Dubbo study) cohort data focusing on genetic changes—including some associated with autoimmunity such as the inflammasome, IL6, IL1beta, IL10, and others—reaffirmed these earlier findings and findings are presented in this special edition of Frontiers in Neurology in “Predictors of chronic fatigue syndrome and mood disturbance after acute infection.” To put it simply: the severity of the initial insult or shock to the body's homeostasis is the best predictor of whether an individual goes on to develop CFS/ME. In the mini-review “Animal models for neuroinflammation and potential treatment methods,” Tamura et al., states the onset of CFS/ME in animals is often associated with neuroinflammation which follows either bacterial or viral infections and it is the degree of neuroinflammation that correlates with the severity of several CFS/ME symptoms

(Bolding is me adding explanation for the abbreviation)

 

[Andy]

This editorial is for the research topic "Infectious and Inflammatory Mechanistic Underpinnings of CFS/ME" in Frontiers in Neurology, other publications in it are (at time of posting)

Lessons From Heat Stroke for Understanding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2021, Stanculescu, Bergquist et al.

Molecular Mechanisms of Neuroinflammation in ME/CFS and Long COVID to Sustain Disease and Promote Relapses, 2022, Tate et al.

Animal Models for Neuroinflammation and Potential Treatment Methods, 2022, Tamura et al

Predictors of Chronic Fatigue Syndrome and Mood Disturbance After Acute Infection, 2022, Sandler, Lloyd et al

Protocol: Multimodal MRI of myalgic encephalomyelitis/chronic fatigue syndrome: A cross-sectional neuroimaging study 2022 Shan et al

 

[NelliePledge]

A R Burton (of Sydney ) has previously published with A Lloyd which presumably explains the use of CFS/ME.

Fukuda is on the panel of editors for this research topic