Fecal Microbiota Transplantation Improves Clinical Symptoms of Fibromyalgia: An open-label, Randomized, Nonplacebo-Controlled Study, 2024, Fang et al.

Discussion in ''Conditions related to ME/CFS' news and research' started by forestglip, May 14, 2024.

  1. forestglip

    forestglip Senior Member (Voting Rights)

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    https://www.sciencedirect.com/science/article/abs/pii/S1526590024004553

    Abstract
    I can't access the full study, but based off Jarred Younger's summary on Youtube, this seems promising.

    45 total participants. Active group received FMT + duloxetine. Control group received only duloxetine. Primary outcome was 0-10 pain scale:

    upload_2024-5-14_17-24-22.png
    Even at 12 months when the study ended, it looks like the FMT+duloxetine group's pain was continuing to decrease below 2, while the duloxetine-only group plateaued at 1 month at about a score of 4.

    Younger said the authors speculate that the duloxetine helps the FMT to have such a profound effect because of serotonin or some-such.
     

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