wastwater
Senior Member (Voting Rights)
Regulation of Foxo1 expression is critical for central B cell tolerance and allelic exclusion
Multi-omics analysis identifies FoxO1 as a regulator of macrophage function through metabolic reprogramming - Cell Death & Disease
Macrophages are plastic cells that can switch among different states according to bioenergetic or biosynthetic requirements. Our previous work demonstrated that the transcription factor Forkhead Box Protein 1 (FoxO1) plays a pivotal role in regulating the function of macrophages, but the...
www.nature.com
I suspect genetically I may produce defective B cells and wondered what effect this may have