Lessons From Heat Stroke for Understanding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2021, Stanculescu, Bergquist et al.

I was recently going down rabbit holes looking at similarities between long term effects of heat stroke or serious heat "exhaustion", which I gather can be much more serious than it sounds but also not necessarily dramatic and sudden enough to raise the serious alarm. I had most of the symptoms of heat exhaustion and some of the symptoms of heat stroke when my first recognizable symptoms started (during and after crossfit) so I've always wondered if there was a link.

After the 'onset' I went to the GP, who said try going for a walk instead of gym, and offered anxiety medication.

 

(relating to first message) Fair enough, but please, NOT on non-humans. Such studies do not advance medical knowledge.

 

If only we were rodents, all of our medical problems would be much easier to treat!

 

my illness began with a fever that lasted for the best part of 14 days so from my point of view some parts of the mechanisms of heatstroke may well overlap in m e . just to add i guess it was a pretty high fever because i have very little memory regarding those 14 days with Beijing flue .

 

I wonder why was there no mention of high fever in the paper? Wouldn't that potentially have similar effects to heat stroke, if overheating is at least part of the problem?

 

Ahh, I remember it well...
The hot summer of 2018. I worked a physical 12 hour day in sweltering conditions. That night I thought I had heat stroke, but it was pem, my first time.
We've been together ever since

 

No, heat underlies heat stroke.

Not that I am aware of.


Time to stop making things up as you go along, guys. There are real live patients out there.

 

They say hot weather reduces exercise performance but mine incrased dramatically after an initial period of adjustment. Instead of interfering it seemed to normalize things.

 

I can't say specifically much about any concept like - and especially in this paper - the leaky gut problems (which seems to be a crushingly important health issue in the occasional paper and then never show up again, surely we can determine if we're all walking around poisoned by LPS bacteria?) but the methods used to link the two conditions could be stretched and applied to pretty much any condition. I appreciate this is probably a thought experiment but if it were a BPS paper it would be tore to shreds. The gene transcription part seems awfully stretched thin. The mitochondrial sectional seems to suggest a completely two unrelated processes, if there is even enough information to be said which probably there is not.

So the conclusions seem doubly stretched.