Abstract Most of the people who suffered from COVID-19 fully recovered, but approximately 10–20% of them developed a wide variety of symptoms after they recover from their initial illness. Long COVID can develop at any patient; however, several studies suggest that the development of Long Covid syndrome may be linked to severity of acute illness. Some of the risk factors are hospitalization (with mechanical ventilation), Intensive Care Unit admission, age (over 50 years), gender (female) and comorbidities. Since the precise mechanism of Long COVID has not been clarified, neither the management of Long COVID-19 syndrome has been solved yet. Promising results have been published with vaccines as they effectively reduced the risk of Long COVID; however, other data suggest that vaccination results only partial protection in the post-acute phase of the disease. Recently, the orally effective antiviral agents (Paxlovid, molnupiravir) are preferred for outpatient management, and they highly reduce the progression of mild-to-moderate COVID-19 to severe one, and consequently, might reduce the development of Long COVID. Finally, recently, several clinical trials are in progress with either dietary supplements or drugs with different mechanisms of action. Additional information on the precise mechanisms, risk factors of Long COVID may result in successful preventive and therapeutic management of Long Covid 19 syndrome. Open access: https://link.springer.com/article/10.1007/s10787-023-01204-1
I though this was a pretty decent snapshot in time. Hungarian authors. They do a good job of traversing the research to date and conveying the lack of epidemiological clarity and the uncertainty about etiology and treatments. Tables 2 and 3 are nice lists of ongoing and completed treatment trials, some of which are interesting. I didn't see even a whiff of BPS-ishness. What did you think @Wyva?
I was thinking that maybe coming from the field of pharmacy helps with having a more critical eye and being less prone to BPS methodological fallacies.
