Long-lived plasma cell (LLPC) theory - Similarities between CFS and Lupus?

[EndME]

Wait, there’s gonna be another trial? I thought they decided against it

I'm not sure what I was writing about here anymore. At least it seems to me now that "Dara" should read "Cyclo" or at least I can't remember a further "Cyclo" trial being planned.

 

[ryanc97]

Is it possible that the feeling better while sick part of ME is due to downregulating FCRN when sick and antibodies/igg having a shorter half life during this period?

Does fcrn downregulate while being sick?

 

[jnmaciuch]

Does fcrn downregulate while being sick?

Not that I’m aware of.

 

[ryanc97]

I have a hunch it could be due to constricting of blood vessels during fever to produce a stimulant like effect, implying some antibody does the opposite in ME?