Long-term outcomes of pediatric infections: from traditional infectious diseases to long Covid, 2022, Buonsenso et al

[Andy]

Abstract

There is limited evidence available on the long-term impact of SARS-CoV-2 infection in children. In this article, the authors analyze the recent evidence on pediatric long Covid and lessons learnt from a pediatric post-Covid unit in Rome, Italy. To gain a better understanding of the concerns raised by parents and physicians in relation to the potential long-term consequences of this novel infection, it is important to recognize that long-term effect of a post-infectious disease is not a new phenomenon.

Open access, https://www.futuremedicine.com/doi/10.2217/fmb-2022-0031

 

[Kalliope]

It shares three patient experiences. One with long covid and two with ME.

 

[Kalliope]

(my bolding)

Conclusion
There is increasing, emerging evidence that children can be affected by long-term SARS-CoV-2 sequelae and post-Covid condition, although at a lower rate compared to adults.

Studies show that most children recover spontaneously within the first six months, but not all.

Studies indicate that the risk is higher in older children.

Even for those that recover, long Covid may have implications in terms of socializing and education and they may need additional support to catch up with their peers.

Moreover, with our increased understanding of potential pathological mechanisms behind long Covid, it is important that long term sequelae in children are not dismissed as psychological problems.

It is important to offer these children comprehensive diagnostic assessments, care and support.

Also, recognizing long Covid as a possible outcome of SARS-CoV-2 infection (in the general population, and in children), will enhance our ability to assess benefits and risks of preventive measures, such as vaccination (Figure 5).

Funding for research into etiology of long Covid and interventional treatment trials including children and adults is urgently needed to inform treatment strategies and improve long term Covid patient outcomes.

Understanding long Covid, its pathogenesis, diagnostic pathways and best management, offers a unique opportunity to also improve our understanding of other post-viral syndromes.

Ultimately, this will have a positive impact on the health of a very large number of people with chronic, undiagnosed diseases, struggling to access appropriate care.