Preprint ME/CFS and PASC Patient-Derived Immunoglobulin Complexes Disrupt Mitochondrial Function and Alter Inflammatory Marker Secretion, 2025, Prusty et al

ChronicallyOverIt said:
Isn’t that classic p-hacking? Our first hypothesis didn’t significantly provide results since some cells didn’t fragment so we narrowed our search window and now the women’s group is extremely significant with all mitochondrial fragmentation.
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I wouldn't say so. They did find high statistical significance (p=0.0004) in the first test, and then it's very legitimate to explore subsets to find out what drives this. (But in general there appears to be plenty of p-hacking here)
 
Siebe said:
I wouldn't say so. They did find high statistical significance (p=0.0004) in the first test, and then it's very legitimate to explore subsets to find out what drives this. (But in general there appears to be plenty of p-hacking here)
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As in in DecodeME, or genetics in general?
Edit: I thought I was in another thread. Ignore this!
 
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