OMF/Ron Davis Research Update December 2017

[Liv aka Mrs Sowester]

Not up to date on this thread, but at my OI onset my FBC showed sticky blood.

 

[Helen]

problems with blood sugar regulation seem to be common among patients

Agree, but it could be caused by low cortisol, that also is common, so I think blood sugar should be tested together with a saliva cortisol test ( more reliable than serum cortisol).

 

[Amw66]

Whether it's an allergic/toxic reaction to something or more akin to a wild blood sugar level excursion is an interesting question. It may have been misleading for me to have used the word "analphylactic reaction" above, as I think the same symptoms might be produced by a lot of adrenalin flooding the system. The symptoms have suggested to me an exaggerated response to "sugar" (glucose? fructose?). Initially, following the ingestion of HFCS, I'd get a shaky/ill feeling that seems similar to what people describe in hypoglycemia, as if a lot of insulin had been released in response to high blood sugar. Then I'd get the flushing, pounding heart, polyuria, etc... which seems consistent with the release of adrenaline to combat low blood sugar, but this did seem like it was a particularly wild swing (I actually still think of this incident 30 years ago as the closest to death that I've ever come).

Yet, my previous glucose tolerance tests were all normal, and my reactions during those tests were not nearly as severe as during this HFCS incident. Oddly, I could (and still can) consume things containing regular corn syrup without effect.

I think my sensitivity to HFCS may have diminished over the years, but I have no intention of putting it to the acid test by drinking an HFCS soda on an empty stomach before breakfast.

How does fructose get processed- from memory it' s dealt differently in the liver from other sugars and that may explain the effect. Fruit is packaged naturally with fibre to slow down its digestion. Whacking your liver with neat fructose may be more than it can deal with, particularly if there are toxins/ other compounds for liver to deal with at the same time.