Persistent postural-perceptual dizziness (PPPD): a common, characteristic and treatable cause of chronic dizziness (2017) Popkirov, Staab, Stone

Esther12

Senior Member (Voting Rights)
I wasn't planning to post this, and was only skimming through, but was blown away by the combination of confidence and low quality evidence in this new piece and thought it could be of interest to others (@Woolie ?).

Persistent postural-perceptual dizziness (PPPD) is a newly defined diagnostic syndrome that unifies key features of chronic subjective dizziness, phobic postural vertigo and related disorders. It describes a common chronic dysfunction of the vestibular system and brain that produces persistent dizziness, non-spinning vertigo and/ or unsteadiness. The disorder constitutes a long-term maladaptation to a neuro-otological, medical or psychological event that triggered vestibular symptoms, and is usefully considered within the spectrum of other functional neurological disorders. While diagnostic tests and conventional imaging usually remain negative, patients with PPPD present in a characteristic way that maps on to positive diagnostic criteria. Patients often develop secondary functional gait disorder, anxiety, avoidance behaviour and severe disability. Once recognised, PPPD can be managed with effective communication and tailored treatment strategies, including specialised physical therapy (vestibular rehabilitation), serotonergic medications and cognitive-behavioural therapy.

http://pn.bmj.com.sci-hub.tw/content/early/2017/12/09/practneurol-2017-001809
 
At what point did the meaning of "functional" go from "it's happening but we can't yet identify the cause" to
"it's happening but we can't yet identify the cause so you must be imagining it"?

Being dizzy is not funny. One cannot talk/think oneself into or out of it. Period.

Also, using the broad brush of "maladaption" is just lazy and rude. The body is wise, and usually adapts
in the most optimal way available to it. Yes, a person's relationship with an ongoing condition can sometimes use some fine-tuning, but to be honest most chronics have that sorted after living with [X] for a while.

So sick of these people focusing on imaginary "disorders" and their fantasy "treatment" counterparts.
 
Of course the vestibular rehab is just there to deflect sarcastic comments about treating every(censored) poorly understood illness in the exact same manner as depression, with CBT and SSRI's.
And is surely the cause of any remission of symptoms obtained.
 
I don't know if it is related to this paper, but in this 2014 paper doctors at Mt. Sinai School of Medicine, New York, apparently found a remarkably effective treatment for a type of "bobbing" dizziness known as Mal de Debarquement Syndrome (MdDS). This is a type of dizziness that some people get after getting off of a moving vehicle like a boat or train. It usually goes away, but, in some people, it can last for years.
We posited that the maladapted rocking and the physical symptoms could be diminished or extinguished by readapting the VOR [vestibulo-ocular reflex] . Subjects were treated by rolling the head from side-to-side while watching a rotating full-field visual stimulus. Seventeen of the 24 subjects had a complete or substantial recovery on average for approximately 1 year. Six were initially better, but the symptoms recurred. One subject did not respond to treatment. Thus, readaptation of the VOR has led to a cure or substantial improvement in 70% of the subjects with MdDS. We conclude that the adaptive processes associated with roll-while-rotating are responsible for producing MdDS, and that the symptoms can be reduced or resolved by readapting the VOR.
http://journal.frontiersin.org/article/10.3389/fneur.2014.00124/full

This finding was also discussed here: https://www.eurekalert.org/pub_releases/2014-08/tmsh-nt080714.php

The dizziness described is of the same character as the dizziness that marked the onset of my ME/CFS - however, mine came out of the blue and was not precipitated by any kind of unusual motion in a vehicle or anything else.

The treatment sounds like something they'd do to No. 6 in "The Prisoner" TV series. You sit in a chair as your head is tilted from side to side. Meanwhile, rotating bars are projected on a screen in front of you.

I have no idea if this would help dizziness in ME/CFS. It sounds bizarre, but apparently it works in many cases of MdDS.

fneur-05-00124-g001.jpg
 
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I wasn't planning to post this, and was only skimming through, but was blown away by the combination of confidence and low quality evidence in this new piece and thought it could be of interest to others (@Woolie ?).
Argh, so annoying. I've heard of phobic postural vertigo before, I was asked to get involved in a study. Thought it was a crock then, but I now wish I had actually got involved, if for nothing else than to help save these poor patients from this psycho-BS.

Look at this:
Isr Med Assoc J. 2003 Oct;5(10):720-3.
Phobic postural vertigo: a new proposed entity.
Pollak L1, Klein C, Stryjer R, Kushnir M, Teitler J, Flechter S.

BACKGROUND:
Dizziness and vertigo can be a complaint in various psychiatric conditions where it usually constitutes only one of the features of the syndrome. Lately, a somatoform disorder characterized by almost mono-symptomatic dizziness and unsteadiness has been described. Since phobic postural vertigo usually presents without anxiety or other psychological symptomatology, patients with this condition seek help at neurologic and otolaryngologic clinics where they are often misdiagnosed as suffering from organic vertigo.

OBJECTIVES:
To present the clinical features of 55 consecutive patients diagnosed with phobic postural vertigo at our clinic during 1998-2002.

METHODS:
We conducted a retrospective review of patients' medical records and report two typical cases for illustration.

RESULTS:
The patients presented with complaints of unsteadiness with or without dizziness, and attacks of sudden veering that caused them to grasp for support. Accompanying anxiety was admitted by only 5% and vegetative symptoms were reported in 18%. In 16% the symptoms resulted in avoidance behavior. A stressful life event or an unrelated somatic disease triggered the onset of PPV in 35% of patients, whereas a vestibular insult preceded the symptoms in 13%. The mean duration of symptoms was 26.7 +/- 39.1 months (range 0.5-20 years). In 72% of patients the symptoms resolved after the psychological mechanism of their symptoms was explained to them; 24% improved with antidepressant treatment (selective serotonin reuptake inhibitors or tricyclic antidepressants), and only in 4% did the symptoms persist.

CONCLUSIONS:
Since PPV is a frequently encountered diagnosis at some specialized dizziness clinics, familiarity with this entity resulting in early diagnosis can avoid unnecessary examinations and lead to effective treatment.
:rofl::rofl::rofl::rofl::rofl:!!

"Once we explained it to them, they said 'hey wow, I never realised I was just nuts and imagining it all, now you've explained it to me I feel totally fine!'"

These guys live in a world where the wise doctor simply "knows" all our follies and our misconceptions and their wisdom is all that's needed to make us better. Is that overoptimism or just pure and simple arrogance?

Btw, they offer no support at all for that 72% figure that were said to have recovered just by being told they were nuts. The paper says 36%, and the measure on which it is based is not explained.

Oh, and that seems to be crap about the patients having comorbid psychiatric problems. The power of confirmation bias, eh? Do you think if I point out to these neurologists the faulty basis of their beliefs, they will make a complete recovery and stop banging on about this being a mental problem? Or is the wisdom only allowed to flow in the other direction?
 
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