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Post-Acute COVID-19 Symptoms, a Potential Link with [ME/CFS]: A 6-Month Survey in a Mexican Cohort, 2021, González-Hermosillo et al

Discussion in 'Epidemics (including Covid-19)' started by Andy, Jun 9, 2021.

  1. Andy

    Andy Committee Member (& Outreach when energy allows)

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    Abstract

    The aim of this study was to describe the clinical evolution during 6 months of follow-up of adults recovered from COVID-19. We tried to determine how many met the definition of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). A total of 130 patients (51.0 ± 14 years, 34.6% female) were enrolled. Symptoms were common, participants reported a median number of 9 (IQR 5–14) symptoms. Fatigue was the most common symptom (61/130; 46.9%). Patients with fatigue were older 53.9 ± 13.5 years compared with 48.5 ± 13.3 years in those without fatigue (p = 0.02) and had a longer length of hospital stay, 17 ± 14 days vs. 13 ± 10 days (p = 0.04). There was no difference in other comorbidities between patients with fatigue and those without it, and no association between COVID-19 severity and fatigue. After multivariate adjustment of all baseline clinical features, only age 40 to 50 years old was positively associated with fatigue, OR 2.5 (95% CI 1.05–6.05) p = 0.03. In our survey, only 17 (13%) patients met the Institute of Medicine’s criteria for “systemic exertion intolerance disease,” the new name of ME/CFS. In conclusion, in some patients, the features of post-acute COVID-19 syndrome overlap with the clinical features of ME/CFS.

    Open access, https://www.mdpi.com/2076-3425/11/6/760/htm
     
    Dolphin, Michelle, Wyva and 3 others like this.
  2. Ariel

    Ariel Senior Member (Voting Rights)

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    Glad there is a discussion of the effect of different diagnostic criteria on their findings in section 3, where they specify percentages for different case definitions of ME/CFS.
     
    Dolphin, Wyva and Andy like this.
  3. Louie41

    Louie41 Senior Member (Voting Rights)

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    I find it almost impossible to read large blocks of text link this. Could the text be broken up? @Andy

    I appreciate all the time you take to find and post articles, and I almost faint when confronting those with large blocks of text.
     
    Mij likes this.
  4. strategist

    strategist Senior Member (Voting Rights)

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    13% is close to what has been found in other infectious illnesses.
     
  5. Dolphin

    Dolphin Senior Member (Voting Rights)

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    Andy likes this.
  6. Andy

    Andy Committee Member (& Outreach when energy allows)

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    From the above detail, I think we can safely assume they are applying the definitions incorrectly somehow.
     
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