Staphylococcus aureus Bacteraemia: A Hidden Factor in the Pathogenesis of Human Disease, JA Morris (2017)

[Samuel]

idk where to post this, and idk what value it has.

it has been claimed in an online comment to be relevant to

[1] cytokine storm on
https://theconversation.com/coronavirus-why-are-some-people-experiencing-long-term-fatigue-141405

"A number of strains produce pyrogenic toxins which are the likeliest cause of the cytokine cascade in Covid-19"

and [2] suggested to be related to long covid in the same place

and [3] itself says it is relevant to chronic diseases.

with a [4] possible whiff of alternativeness [by which i mean idk anything about what body of research lies behind it].


the paper is

https://www.jscimedcentral.com/Microbiology/microbiology-5-1037.pdf

and https://www.jscimedcentral.com/Microbiology/vol5issue1.php for non-pdf.


"The research programme that we should pursue is therefore
clear. Measure urinary IgG, serum inflammatory markers and
faecal carriage of S. aureus in a wide range of chronic diseases.
If there is evidence of increased staphylococcal carriage and
staphylococcal bacteraemia then encourage the patient and family
members to consume yoghurt (natural, live, no added sugar, full
fat) on a daily basis thereafter."

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given that at least one of the m.e. cytokine studies [wpi i think] reported particularly high il-6 and high il-8 in one m.e. cohort, i wonder if that is relevant to covid cytokine storm or long covid in a subset of pwme.

also i wonder whether undetected existing upper respiratory staph colonization or infection could be relevant to m.e.

===

ETA: it looks like a prospective study reported transient high il-6?: https://theconversation.com/chronic-fatigue-syndrome-new-evidence-of-biological-causes-108854

 

[Samuel]

p.s. in my own case i have a long term refractory nasopharyngeal colonization of staph aureus. it was made worse by, and detected by, a nasopharyngeal swab [a kind with hooks].

this paper if it has any relevance to anything might suggest some pwme might have staph someplace.

i was also tested by blood by an intramural nih lab to have high inflammatory cytokines, including high single-digit il-6, tnf alpha in low double digits, and an il-8 level greater than 1000 [!].

i was told that the cytokines i was tested for were all supposed to be in single digits, not quadruple.

 

[Amw66]

High staph aureus in GI map test last year. Have had no further testing. ( a few high and low markers including C Diff )

Practitioner advised that she sees high staph aureus commonly with clients with anxiety/ autism.