Symptom-based Rehabilitation Compared to Usual Care in Post-COVID - a RCT (RELOAD) 2021/22 Germany

[Sly Saint]

Recruitment Status : Not yet recruiting

Sponsor:
Schön Klinik Berchtesgadener Land
Collaborators:
Bavarian State Office for Health and Food Safety
Praxis im Zentrum Erlangen
Pneumologen Lichterfelde Berlin
Pneumopraxis Marburg
COVID ambulance Philipps-University Marburg
Pneumologie Elisenhof Munich
COVID ambulance Pneumology LMU Munich
COVID ambulance psychology LMU Munich
University Clinic Augsburg
COVID ambulance Schön Klinik Schönau
Information provided by (Responsible Party):
Prof. Dr. Andreas Rembert Koczulla, Schön Klinik Berchtesgadener Land


Brief Summary:
Inpatient, multimodal rehabilitation represents one of the most important interventions in the disease management of post/long COVID. Different professional societies, including the German Society of Pneumology and the European Respiratory Society, recommend rehabilitation intervention to reduce the sequelae of COVID-19. However, from the perspective of science and practice, there are relevant areas that have been insufficiently investigated and are essential for the treatment success of post/long COVID patients:

• Differentiation of rehabilitation effects from natural recovery after COVID-19.
• Lack of personalized and symptom-based treatment approaches that can address the heterogeneity of symptoms in post/long COVID
• Lack of uniform, high-quality rehabilitation standards in post-/long-COVID.

Therefore, the primary objective of this randomized controlled trial (RCT) is to investigate whether a 3-week symptom-oriented, inpatient, multidisciplinary rehabilitation intervention, whose content focus is standardized according to cluster assignment (fatigue, cognition, soma), has a positive effect on the quality of life (primary outcome) in post-COVID syndrome patients compared to a usual care group (standard outpatient care). All study participants will be provided with a continuous telemonitoring system (SaniQ app) throughout the study period. After the interventional phase, there will be a 3 months follow-up assessment to evaluate the maintenance effects of COVID rehabilitation.

https://clinicaltrials.gov/ct2/show/NCT05172206

 

[Sean]

Inpatient, multimodal rehabilitation represents one of the most important interventions in the disease management of post/long COVID.

I look forward to the evidence for that claim.

Lack of uniform, high-quality rehabilitation standards in post-/long-COVID.

I look forward to the evidence for that even more.

All study participants will be provided with a continuous telemonitoring system (SaniQ app) throughout the study period. After the interventional phase, there will be a 3 months follow-up assessment to evaluate the maintenance effects of COVID rehabilitation.

Sounds promising, though 3 months is too short, needs a minimum of a year.