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T cell immunomodulation by bile acid metabolites, 2020, Giovannini et al

Discussion in 'Other health news and research' started by Andy, Feb 12, 2020.

  1. Andy

    Andy Committee Member

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    22,420
    Location:
    Hampshire, UK
    A short review/opinion piece.
    Paywall, https://onlinelibrary.wiley.com/doi/pdf/10.1111/all.14223
    Sci hub, https://sci-hub.se/10.1111/all.14223

    @mariovitali , another one that will probably interest you. :)
     
    Andy, Feb 12, 2020
    #1
    rvallee, MeSci, ScottTriGuy and 2 others like this.
  2. Amw66

    Amw66 Senior Member (Voting Rights)

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    Amw66, Feb 12, 2020
    #2
    mariovitali likes this.
  3. mariovitali

    mariovitali Senior Member (Voting Rights)

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    506
    Thank you for the mention @Andy and @Amw66.

    I do know that Derya Unutmaz was supposed to be looking more into Bile acids. He is usually responsive and so i will try to find out whether he thinks that Bile acids metabolism deserves more attention given their importance to TRegs and TH17.

    I fear however that the observed disruption of TRegs and TH17 is very likely to be non-ME specific. I feel that we need to check whether TH17/Tregs findings differentiate ME patients from other patients with autoimmune disorders (e.g colitis, psoriasis, RA) :


    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877591/
     
    mariovitali, Feb 12, 2020
    #3
    ukxmrv, rvallee, MeSci and 2 others like this.

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