I had all these panels of tests done over 25yrs ago and had a consult with a biochemist regarding my results. He owned a compounding pharmacy and tailored a 'custom formula' based on my results. I was deficient in most vitamins, proteins, fats, high oxidative stress et, but only omega-3 fish oils and magnesium/taurine injections improved my energy levels. It was pretty instant too.
His "hypothetical disease model" has been tried and done over and over again since the late 90s, and yes there are some hit and misses if you want to waste a lot of money on hope in a bottle.
"Some key mechanisms -
1) PEM explained primarily as impaired glycogen storage -> frequent glycogen depletion, downstream of multiple mechanisms, some key influences being sympathetic overdrive, low intracellular mineral status and histamine.
2) Baseline worsening created by pushing through PEM is caused by lactic acid metabolism -> acidaemia / acidosis -> enhanced renal excretion of zinc and electrolytes + inflammatory signalling cascade that inhibits absorption of dietary minerals.
3) Gut fermentation syndrome -> chronic acetaldehyde -> wide cascade of impairments, endogenous opioid synthesis and dysregulated cAMP-PKA.
4) Dysautonomia and extracellular ATP alarm signalling vs low dampening signal (inosine)... and quite a range of other impairments explained in the cascade".