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  1. Sean

    ME/CFS Research Chatbot

    It is not just the GIGO problem, AI thus far has not shown any great capacity to independently reason, including understanding methodology and context. At this point it is little more than a fancy collator and summariser. Still does not in any sense understand the actual content of the material...
  2. Sean

    Academic publishing: a discussion

    More than a little ironic that peer review was not peer reviewed before it became the entrenched wisdom. And not for a long time after it was either.
  3. Sean

    Australia: National Health and Medical Research Council (NHMRC): Development of ME/CFS guidelines

    By their co-authors shall ye know them. Sandler seems to be the BPS rep on the panel.
  4. Sean

    How should biological researchers present their results about ME/CFS to the media - discussion thread.

    More like they think it is anxiety about non-symptoms, about misinterpreting normal somatic signals and sensations (e.g. DOMS). Exactly. It is dishonest and underhanded in the extreme for the psychs to claim that being worried about a life-destroying change in health status, with no...
  5. Sean

    Preprint Understanding Neuroinflammation in Post-COVID-19 Syndrome: Biological Mechanisms, Diagnostic Biomarkers, and Therapeutic..., 2025, Martins et al.

    His excuse for that will probably be along the lines of not wanting to inflame an already volatile situation. I mean, we wouldn't want the professor to face awkward impertinent questions from his victims about his role in creating that situation in the first place, would we.
  6. Sean

    How should biological researchers present their results about ME/CFS to the media - discussion thread.

    Yep. It might be disheartening and frustrating to have deal with the psycho-political stuff, but it has to be done. Also, from the paper: Expect wilful misinterpretations of that term. Something like 'exercise phobia' might have been better. ––––––––– Psychobehavioural is a better term than...
  7. Sean

    Preprint Understanding Neuroinflammation in Post-COVID-19 Syndrome: Biological Mechanisms, Diagnostic Biomarkers, and Therapeutic..., 2025, Martins et al.

    His own website describes exactly how he wants his work on ME/CFS to be seen, and his bravery in standing up against the hordes of militant anti-psych patients. Let's just say that there are other, less selective and less flattering, interpretations of it...
  8. Sean

    Who is Simon Wessely?

    Don't know how long ago he wrote that.
  9. Sean

    Replicated blood-based biomarkers for Myalgic Encephalomyelitis not explicable by inactivity, 2024, Beentjes, Ponting et al

    Not to mention whether or not patients looked down the barrel of that psychosomatic gun in a sufficiently manly manner. It's a nice compare and contrast. Leaving aside the question of how accurate that claim is, how is he reliably discriminating the critical issue of which causal pathway...
  10. Sean

    Reddit - Interesting posts on Reddit, including what some doctors say about ME/CFS

    Phew, what a massive arsehole. :grumpy: I see he is an orthopaedic surgeon, which specialty has [checks notes] absolutely nothing to do with ME/CFS. On the good side, the fact that he is so open and abusive and extremist means he will have precisely zero room for excuses when the time for...
  11. Sean

    Replicated blood-based biomarkers for Myalgic Encephalomyelitis not explicable by inactivity, 2024, Beentjes, Ponting et al

    re: BMI effects on ALP My single data point is that my ALP has remained in the same range independent of my BMI (which was ≈22-25 for the first 25 years of ME/CFS, then rising slowly to ≈28-30 over the 15 years or so since).
  12. Sean

    Replicated blood-based biomarkers for Myalgic Encephalomyelitis not explicable by inactivity, 2024, Beentjes, Ponting et al

    I have persistently high ALP. It was first noted in my initial diagnostic workup for ME/CFS in 1989, and has been high every single time it was measured since then (including routine annual bloods).
  13. Sean

    New version of Covid, called NB.1.8.1 or Nimbus, doing the rounds

    Something I have done since the early days of Covid, when the basic symptom profile was becoming clear, was keep a few packets of the anesthetic type throat lozenges in stock. Have not had to use them yet. But still have them and replace them when past their use-by date.
  14. Sean

    [Book chapter] How Stigma Emerges and Mutates: The Case of Long COVID Stigma, 2025, Farrimond et al

    Plain English should be compulsory in the first year of all undergraduate degrees.
  15. Sean

    Preprint Understanding Neuroinflammation in Post-COVID-19 Syndrome: Biological Mechanisms, Diagnostic Biomarkers, and Therapeutic..., 2025, Martins et al.

    Nah. They will just twist the results to something like claiming that such findings are secondary consequences of avoiding activity, of the dysregulated psycho-neuro state, etc. Whether they can continue being successful in doing so is another question.
  16. Sean

    DWP assessor reveals 'sneaky' tricks used in PIP exam such as chair choice test

    Trust is the most important element of the clinical encounter. Betray that, and it is all over.
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