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Bit pointless without controls.

Is the middle aged thing a post hoc analysis? The abstract makes it sound like the prespecified analysis was null so they went fishing.

I had a rather similar experience in the first few years of my illness. At the peaks I never quite got good enough to resume normal life, but after improving for several months and starting to dream about being recovered again, the crashes were emotionally hard to take. I eventually noticed the...

Surely it's a complete nonsense to place any significance on A being twice B if A and B are not statistically significantly different. How did they get away with saying that?

Someone close to me suffers terribly from anxiety and your description is spot on. Just because CBT has been abused in our case doesn't mean it is never useful.

But we know the general population data for SF36 PF is non normal due to hitting the ceiling of 100 for healthy people. (Eg. The first hit on a google search for "sf36 physical functioning non normal distribution" is https://www.ncbi.nlm.nih.gov/m/pubmed/17515490/ ) So do any of these...

I just created the histograms below from the baseline (all groups) PACE data. The CFQ data is definitely skewed but interestingly the SF-36 PF is less so I guess the Bowling population data is more skewed because healthy people have a strong ceiling effect but sick people less so.

That desk definitely looked staged. I'm sure nobody actually works at it like that. Microscope and glass flasks?!

I get the point about using the general population rather than the presumably narrower patient group. But we've seen that the distribution of the SF-36 is definitely not a normal distribution. Is it possible to derive something meaningful from the standard deviation of a non- normal distribution?

Alpha particles are stopped by a piece of paper or a few centimeters of air. To do damage you need to ingest something radioactive and have it taken up by your body. I would have thought that would mean there should be a strong association of ME with cancer which I don't think there is.

I guess you mean this: https://en.m.wikipedia.org/wiki/Tay_(bot)

The thrust of the article seems to be that if the current system is so full of biases based on race and socio economic status, it can not be relied on to train the new AI systems. Using current practice to train AI systems will result in an AI system that entrenches the current biases.

Unfortunately I suspect that, from within their bubble, they sincerely believe that truth is on their side.

I think this misses the point. If a RCT shows a positive effect using an intervention that we know is totally implausible (e.g., homeopathy) then there must be something wrong with the way the trial was conducted (e.g., subjective endpoints and unblinded). What is needed is for these bad...

So they're saying two measures agreed (and gave a null result) and one differed so therefore the one that differed must be correct and the other two are wrong for reasons? You couldn't make this stuff up!

A quick google gives me this. It looks like it is from a company that provides medical indemnity insurance. I have no idea if it is accurate. (https://www.mdanational.com.au/advice-and-support/library/blogs/2017/07/recording-consultations)

This certainly agrees with my experience. I tend to have more problems cognitively than with muscles, so I can manage ok with medium walks on flat terrain. But as soon as the ground starts sloping up a little I must slow right down. If I slow down enough I can then keep going uphill. So it...

Just a bit before it said So it's therapists opinions.

Actually, in the mediation analysis paper (Chalder et al, 2015 https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(14)00069-8/fulltext) they adjusted the Borg scale by dividing by the post exercise heart rate. The appendix to that paper (available as a pdf from the link above)...

I first had this strike out of the blue this time last year. I've had ME for 25 years and am in my late 50's. It was not a pleasant experience. The first episode was pretty bad, to the point where I called for an ambulance since I had no idea what it was and couldn't walk to the car so someone...