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  1. Sean

    David Tuller: Trial By Error: An Open Letter to The Lancet, Two Years On

    Thank you, @Lucibee Being able to do the correlation calculations is the most powerful argument for the full (anonymised) data set being released, at least to independent statisticians, if not publicly. (And Cochrane's behaviour has ruled themselves out as independent.) Can you post a higher...
  2. Sean

    A general thread on the PACE trial!

    No, PACE was not controlled. It was described as 'controlled' in the PACE protocol paper (2007), but not in the main paper (2011). Which means that either the PACE authors decided not to claim controlled status, or it was denied to them by the reviewers or journal editors. The word...
  3. Sean

    Video: The PACE trial: a short explanation, Graham McPhee

    Those Physical Functions responses look like standard decay curves. That is, what you would expect from regression to the mean and a null hypothesis. Same for the Fatigue Scale too (for all participants).
  4. Sean

    David Tuller: Trial by Error: Sir Simon Scores an Own Goal

    Not to mention a well above average income stream.
  5. Sean

    David Tuller: Trial By Error: An Open Letter to The Lancet, Two Years On

    I want to see the correlation calculations between the subjective self-report and the objective outcomes. That is what will seal the deal.
  6. Sean

    Michael Sharpe skewered by @JohntheJack on Twitter

    So what the effing eff do you think the dozens of serious considered letters from patients to the journals pointing out technical flaws were attempting to do with you and your co-authors? And you guys just blew us off with evasion, misdirection, and insult. Now you demand a sensible dialogue...
  7. Sean

    Michael Sharpe skewered by @JohntheJack on Twitter

    re Saving Tweets. If you load the entire Twitter thread you should then be able to save it all as a single PDF document, via the Print function of your browser. Much better than a zillion screen snaps. Then just update every so often, as required.
  8. Sean

    Michael Sharpe skewered by @JohntheJack on Twitter

    Always had my money on Wessely being the first rat off the ship. Sir Professor Simon Wessely, co-recipient of the inaugural John Maddox Prize for Courage in Standing Up For Science, is a gutless coward. Maddox would be turning in his grave. Most important of all, the basic causal...
  9. Sean

    Michael Sharpe skewered by @JohntheJack on Twitter

    I suggest that the hypothesis/model underlying CBT and GET used in PACE is falsifiable via the correlations (or lack of them). No correlations between subjective self-report outcomes and objective outcomes equals no causal connections, therefore no effect from the treatments. We already know...
  10. Sean

    David Tuller [13/6/18]: A Curriculum for Treating CFS with CBT

    The cumulative (direct and indirect) costs of misdiagnosis and mistreatment must be huge.
  11. Sean

    Mind, Madness and Power - Simon Wessely and others

    I don't distinguish between the two. The line really is arbitrary, far as I am concerned. They are all just psych to me.
  12. Sean

    Michael Sharpe skewered by @JohntheJack on Twitter

    Yep. They have no plausible deniability whatsoever. There is not the remotest possibility they can say they were not warned, repeatedly and going back decades, about the harm they are doing. I am in the camp that thinks it is best to avoid them. They are unnecessary and just give your opponents...
  13. Sean

    Michael Sharpe skewered by @JohntheJack on Twitter

    A cup of tea, a Bex, and a good lie down, as we used to be told by advertising gurus in Australia. It has become a generic put down, meaning stop being a drama queen. Typically used as a feminised insult, because the product was pitched at women. (Bex was a headache 'remedy', in powder form...
  14. Sean

    Improving Access to Psychological Therapies (IAPT) - The Need for Radical Reform, 2018, Scott

    We are well into cult territory with these clowns, and they show no signs of turning back. Throw in a couple unicorns farting fairy floss rainbows, and you got a deal!
  15. Sean

    The Biopolitics of CFS/ME

    The interests of patients outweigh those of all other 'actors' combined. Yet our interests have been by far the least recognised, respected, and served. That must change.
  16. Sean

    Who is Simon Wessely?

    Wessely has made very sure over the decades that his 'advice' is in tune with the contemporary political zeitgeist*, and indispensable to the political and economic establishments. They are all now locked together in a mutual protection racket. If they dump him, they have to face some serious...
  17. Sean

    Michael Sharpe skewered by @JohntheJack on Twitter

    I am as critical of the political class as anybody. But I am more critical of the voters. In a democracy it is ultimately the responsibility of voters to make it work. If it doesn't work, it is because we made poor choices, for whatever reasons.
  18. Sean

    Analysis of data from 500k individuals in UK Biobank shows an inherited component to ME/CFS (Ponting blog)

    Probably best to regard that as a quite plausible but still untested hypothesis at this point. Might be true, might not.
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