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  1. Colin

    ...discrepancies between objective and subjective measurement of the physical activity level in female patients with [CFS], 2021, Vergauwen et al

    Doesn't that mean that there is less of a discrepancy between the self-reporting and the measurement in the older women? So the older women are more accurate in their perception/reporting? And was the length of time that they'd had ME/CFS taken into account? And why was this a single-sex study?
  2. Colin

    Paul Garner on Long Covid and ME/CFS - BMJ articles and other media.

    That's the opposite of gaslighting, surely. And, if you're in a dark, dank, gaslit basement by yourself and you blow out the offendingly-spooky light, the gas will start to rise and... Quick! Someone go down there and get him out of there!
  3. Colin

    Follicular regulatory T cells produce neuritin to regulate B cells (2021) Gonzalez-Figueroa et al

    Summary Regulatory T cells prevent the emergence of autoantibodies and excessive IgE, but the precise mechanisms are unclear. Here, we show that BCL6-expressing Tregs, known as follicular regulatory T (Tfr) cells, produce abundant neuritin protein that targets B cells. Mice lacking Tfr cells or...
  4. Colin

    Should I get an air purifier to cope with dust?

    Quite a few of them have a built-in UV sterilizer. Mine has a built-in, anion generator. I just had a look on eBay for what replacement filters for my unit cost and some are going for under $6. But some other brands advertize that they are "true", Hepa filters and I don't know what the...
  5. Colin

    Should I get an air purifier to cope with dust?

    You'd be surprized by how much can blow in from a distance. I'm also about 20 feet up and at the back of a large building and that makes no difference. It is a matter of how heavy the traffic is and which way the wind is blowing. Regarding cooking, it's quite amazing how the reading...
  6. Colin

    Should I get an air purifier to cope with dust?

    I bought one with a HEPA filter about six months ago as I'd developed some sort of persistent sinusitis. Where I am is near a medium-sized, main road but it's on a hill so cars and trucks brake to stop at the lights outside. It took me years to realize that the dust is probably from the brake...
  7. Colin

    Parkinsonism as a Third Wave of the COVID-19 Pandemic? (2020) Beauchamp et al

    Abstract: Since the initial reports of COVID-19 in December 2019, the world has been gripped by the disastrous acute respiratory disease caused by the SARS-CoV-2 virus. There are an ever-increasing number of reports of neurological symptoms in patients, from severe (encephalitis), to mild...
  8. Colin

    The biology of coronavirus COVID-19 - including research and treatments

    And here is an overview from her, too; in a Vox interview: The scientist who's been right about Covid-19 vaccines predicts what's next
  9. Colin

    News about Long Covid including its relationship to ME/CFS 2020 to 2021

    Vox interview with Hilda Bastian:
  10. Colin

    The Puzzle Solver by Tracie White

    Interview on Australian radio with Tracie White, by Suzanne Hill. It went out tonight across the country, on the ABC's Local Radio network: ABC: Nightlife Segment starts at 1:00:00 and goes to 1:26:40. This recording will be up for only about a week. Edit: This segment has now been put up...
  11. Colin

    Glutamate transporters have a chloride channel with two hydrophobic gates (2021) Chen et al

    Abstract: Paywall: Nature Popular Article (with cool animation): A 'twisted elevator' could be key to understanding neurological diseases
  12. Colin

    Dr Norman Swan: ME/CFS is more psychosomatic than long-COVID

    That was a long time ago. He's been comfortably enscosed at the ABC for a long time since then. The way that Swan got McBride was to quietly accumulate data on him over a period of many years when no-one else in the medical profession would touch it, though many were aware of what was going on...
  13. Colin

    Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes (2021) Sanmarco et al

    Abstract: Astrocytes are glial cells that are abundant in the central nervous system (CNS) and that have important homeostatic and disease-promoting functions1. However, little is known about the homeostatic anti-inflammatory activities of astrocytes and their regulation. Here, using...
  14. Colin

    The chronic neuropsychiatric sequelae of COVID‐19: The need for a prospective study of viral impact on brain functioning (2021) de Erausquin et al

    Open Access: Alzheimer’s & Dementia ATC report on the paper (3m): How COVID-19 Attacks The Brain And May Cause Lasting Damage
  15. Colin

    ME/CFS: Organic Disease or Psychosomatic Illness? A Re-Examination of the Royal Free Epidemic of 1955, Underhill & Baillod, 2020

    Not quite. The 1919 Eddington experiment was widely hailed in the press, immediately afterwards, as spectacular proof of the radical, new theory but it didn't actually prove anything. The observational accuracy just wasn't good enough and there were theoretical alternatives. But the supporters...
  16. Colin

    Investigating reduced tolerance to alcohol in ME?

    N=1 seeks others with a view to forming a statistically-significant cohort. That could well fit my situation as I got into this mess via hepatitis. And that does beg the question of whether the ethanol-intolerants are only a sub-group, the liver damage being only a casual association, it being...
  17. Colin

    Investigating reduced tolerance to alcohol in ME?

    Well that's the problem, isn't it? Where does one get a working hypothsis from? But you may well be right. It might well be premature and maybe something will come out of other research to shed some light on it. I can't imagine anyone getting the money even for a dedicated study as things stand...
  18. Colin

    Investigating reduced tolerance to alcohol in ME?

    Of course there is bias but if there is any bias regarding drinking beer, here, it's way in favour of it, still, despite the known toxic effects. And you would be hard-pressed to convince me that the three days that I spent in bed after the last time I attempted to be normally social by drinking...
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