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From the video:

It also could be the amount of something in the blood. There could be too little (or none) of something in the blood that's necessary, or too much of something that may or may not be necessary but which is toxic at high levels. High on my list of suspects would be some metabolite created by a...

Even if the only use of the nanoneedle technology was its ability to reliably distinguish ME/CFS patients from controls, it would still be a huge step forward for research.

Do you need to belong to Faceboook?

"Consultation-Liaison Psychiatry" used to be called "Psychosomatic Medicine" which was defined as "the psychiatry of the medically ill." In effect, these were psychiatrists who were brought in to consult on psychiatric problems brought on by physical illness. This could include evaluating...

I was kind of thinking that "autonomic hypervigilance" might prevent (central) sleep apnea from occurring in the first place, so they wouldn't see a connection between the two.

This is becoming the longest goodbye since The Who announced their Farewell Tour in 1982.

I wonder if the "autonomic hypervigilance" could be compensating for some kind failure in breathing rhythm while asleep - sort of as an alternative to repeatedly waking and gasping for air.

Shorter is a (cross-appointed) "Professor of Psychiatry" at the University of Toronto. I imagine that many people see him identified as such (as in theconversation.com article ) and just assume that he must be a psychiatrist, or at least some kind of physician. But you know what they say happens...

Curious. The U.S. donation website at https://www.omf.ngo/triple-giving-tuesday-2019/ says: Could the minimum somehow only apply in Europe? ETA: It's not totally clear, but it looks like the minimum may apply if you want to use something called "Gift Aid" in the UK and are donating to OMF...

Interesting that at 16:22 in the Q&A video he mentions a site in the brainstem called the "nucleus ambiguus," which is apparently important in voluntary breathing (according to a "lesion study"). I know that myself and some others have mentioned the sensation of "having to remember to breath"...

I like the short list of symptoms they chose to display. It's very consistent with my experience, except for "chronic infections" (like many, I seemingly became "flu immune" after onset). "Unrefreshing sleep" has always seemed like a big understatement to me. What's a term for feeling worse...

I think he said that if they don't understand the disease well enough to cure it, they should also focus on prevention (as well as finding a biomarker, treatments and gaining a better understanding of the disease). If you have a cure, I suppose prevention isn't entirely necessary, although it...

I suspect that the follow up on this study faltered for lack of funding. Dr. Natelson was certainly making an effort to find funding to move on to the next phase. In that next phase they were going to test the most suspect of the unique proteins from the pooled results against all the...

So what is this application it wants me to download? Presumably safe?

Hmmm.... Googled "mirthful" and got this book from 2006...

This is a great article to have available on-line, particularly because of the association with the Harvard Medical School. It may not be news to the many of us who have been affected by ME/CFS for years and decades, but I'm sure it would have been incredibly helpful to have had something like...

When I heard that last Saturday was the 30th anniversary of the fall of the Berlin Wall, I decided to re-watch "The Lives of Others." I'd seen it in a theater when it came to the US in 2007. It's a really exceptional cold war "thriller" with great work by everyone involved. My only...

I'd suspect that the connection between frequent colds and infections and the risk of ME/CFS is indirect; that is, there's probably not a shared "weakness" that results in both frequent cold/infections and ME/CFS, but rather that ME/CFS is often triggered by colds and infections. The more colds...

It's probably worth remembering that, between the trial and placebo groups combined, 70% of the patients did not respond (105 out of 151). 26% of those who received rituximab (20 of 77), and 35% of those who received placebo (26 of 74) responded, making the combined response rate 30%. I wonder...