Search results

Variation in Repeated Handgrip Strength Testing Indicates Submaximal Force Production in Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Stoyan Popkirov Background Changes in handgrip strength have recently been adapted as clinical biomarkers for myalgic...

“The rising cost of Long COVID and ME/CFS in Germany” – the interview on the study Video in German with English subtitles. The description:

Are they referring to something else when they say "small minority"? 63% is clearly not a minority. They refer to "documented" infection. Is there data on what proportion of these infections in DecodeME were "documented"?

In fact, 90% of points would be expected to be below a -log10 p-value of 1. If looking at the x-axis in the QQ-plot (the expected p-value for each point if it was a null distribution), 90% of points are left of 1 (p>0.1), 99% left of 2 (p>0.01), 99.9% left of 3 (p>0.001), and so on. I...

Yeah I was thinking that most of the photos they recommend just look like people sleeping. If it's hard for people in the life of a pwME to really know what's going on, then trying to capture it in a photo is nearly impossible.

Some posts about very mild ME/CFS have been moved to a new thread: Very mild or prodromal ME/CFS

Yeah, it's exciting! Much more practical than doing surgery every time you want to count a certain type of cell in hard to reach places. I don't know how hard it is to make a tracer for any given molecule, but in the research roadmap webinar, Dr. James showed this with various tracers in use or...

The tracers are certain molecules that release radiation. If they're inside a patient, a PET scanner can detect the radiation which lets you pinpoint the exact location it came from, thus where in the body the tracer is. They make tracers that stick to specific molecules that exist inside...

No I must have misremembered if they're saying they plan to add more males.

I'm not sure exactly what you're referring to. But I think she said they haven't tested in men yet. Edit: Or maybe they did test some? The summary slide says they plan to increase sample size for males.

I assumed the bar plot shows fewer than all the tissues/organs they looked at, and they just picked and chose the tissue groups and bones where there appears to be a pattern (even if not quite significant in some), plus three organs just to demonstrate that it's not high everywhere. Would they...

Jaime Selzer posted several screenshots from his talk on Bluesky, but I think you need to be logged in to see. Is this the one:

In my intro to immunology reading, I thought what happened was that naive B cells that do not match an antigen or do not receive co-stimulation from a T cell die by apoptosis. Are T cells actually directly killing B cells?

Editorial: Dormant Cancer Cells, Cancer Progression, and Post-Acute Sequelae of COVID-19 and Influenza Dinah V. Parums Abstract Since the COVID-19 pandemic, vaccine uptake has fallen, and awareness of the long-term consequences of respiratory virus infections, particularly long COVID, also...

See thread for trial protocol: [USA] A Double-blind, Randomized Study to Evaluate the Efficacy and Safety of Bezisterim (NE3107) in Adults With Long COVID [ADDRESS-LC]

Previous thread: BioVie Awarded up to $13.1 Million in Funding from U.S. Department of Defense to Evaluate Bezisterim (NE3107) for the Treatment of Long COVID

A Double-blind, Randomized Study to Evaluate the Efficacy and Safety of Bezisterim (NE3107) in Adults With Long COVID Brief Summary Long COVID is a condition where debilitating symptoms can persist for months after a COVID-19 infection.This study aims to evaluate the effects of NE3107 on...

In the screenshot I posted of the bar plots of the data for tissues in everyone, it looks like there may be a signal in the bone as well. In the pelvic bone and maybe also in the femur and lumbar bone marrow, though not significant for the last two. Does it change things for there to be signal...

I don't know about the two specific people in the images, but in the demographic data screenshot for all 13 women, for the multidimensional fatigue inventory (MFI) score it says 86.62 for cases and 32.08 for controls. From a paper:

Upper gastrointestinal symptoms and Gulf War Illness in a clinical cohort of US veterans: a retrospective, cross-sectional study Abdelrahman Yousef, Sarah T Ahmed, Theresa H Nguyen Wenker, Alice B S Nono-Djotsa, Stephen H Boyle, Elizabeth J Gifford, Deeksha Malhotra, Helena Chandler, Sandhya...