Search results

It's like trying to share the gravity of ME/CFS to not just healthy people, but to other chronically ill - you have to live with a channelopathy, or live with someone who has one, to grok it.

How many diseases that fall under this umbrella have fingerprints on them?

I wonder who the science advisor was for the Contagion script. :rolleyes:

While it's great to sorta admit there are long-term intractable problems with some infections, and it's great to unite infection sufferers under a kind of support group/banner, and yes, there's power in numbers - I still cannot help feeling "one step forward, two steps back". How'd direct CDC...

Small world. I was recruited for this for the CFS cohort, and also considered for the PTLD part; I declined regardless: And I was in a subsequent one to this below with the Georgetown U folks.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632922/ https://pubs.acs.org/doi/10.1021/pr300577p

Mental illnesses are problems with the brain. I use brain cancer as my rubric. Would I go to a psychiatrist to treat my brain cancer if I developed it? That's just silly. Nor would I go to one if my brain were infected by a pathogen - even if I evidenced mental problems. If psychiatry is...

That lot wears hyperbole like a bad toupee.

Diagnostics suck.

I have found that the math is not a neat math. It's more or less guilt or success by association. My ire is pretty much directed at diagnostics, but I've plenty to go around. There's more than enough for clinicians and researchers who ascribe binary diagnoses to phantom culprits based on...

How do you balance the positives associated with treating possible bacterial infections with the negatives of mitochondrial problems?

Lots of conflicting data out there. Lots. I seem to recall a 2011 or so study which suggested tetracyclines were helpful in some MS cases. But I don't recall if it was ever replicated. And forget about Lyme disease. I've eaten boatloads of doxy and mino. Distressing to think I may have paved...

So this applies to both me and my wife, but no pain for me. And in theory no PEM for my wife, but she gets "episodes" that can occur a day or two or whatever after doing too much. Are episodes PEM? Is it all her symptoms? Hard to tell anymore. I sometimes think this may contribute to the...

Parody of esteem.

Muscle weakness is a hallmark of channelopathies as well. There are more and more channelopathies being identified - or at least labeled as such - without genetic markers, i.e., that have no known genetic marker yet. For instance, my wife has a rare channelopathy that is called ATS1. It is...

Shouldn't the title be "Prevalence of two genetic diseases in ME/CFS patients"? There are many genetic diseases, more than two of which can appear at times similar to ME/CFS. To me, at least, the title suggests all genetic diseases.

I think there may be merit to an Office of IACIR. But this should not be business as usual in terms of selecting the researchers who work there. I think a well-vetted patient task force should be formed that has a large amount of influence into who populates that institution in terms of...

They should be able to tell us. They should have all rickettsial diseases well-characterized by now. They should have unquestionable yes-or-no diagnostics available anywhere any time Rickettsia falls into a differential diagnosis. You can replace "Rickettsia" with any number of infections...

Supposedly Willy Burgdorfer was convinced that what was making all those people get and stay sick back in the late 70's was Rickettsial. No one is really clear on why he changed his mind suddenly to a Borrelia spirochete since he found both in virtually all the same samples from sick...

I know some viruses have a tropism for tissue, e.g. influenza A toward the lungs, but I'm not sure about traces that serology would detect. I do know, however, that some bacteria are tissue-tropic and traces are next to impossible to find in the blood and waste. PCR is hit or miss. Antibody...