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  1. Sean

    How to read while lying completely flat?

    In my experience text-to-speech is very useful in shortish bursts, and I am grateful for it. But it is not so good for extended reads. It gets very drone like and relentless, almost oppressively at times, as it lacks the normal semi-random variations in tone and pace and rhythm found in...
  2. Sean

    Characterization, Treatment, and Long-term Follow-up of Fatigued Patients in Primary Care (iFAS), Lindsäter et al

    As I have been saying for years, psychosomatics has become a cult, and like all cults they are openly hostile to critics and criticism, and will actively reject and suppress all criticism, especially informed accurate criticism. And the more informed and accurate and persistent the criticism...
  3. Sean

    Neurometabolic network NMetNet for functional neurological disorder in children and adolescents, 2025, Lan et al.

    CONCLUSIONS These findings suggest that FND is characterized by dysregulated bioenergetics and increased vulnerability to oxidative stress. Understanding NMetNet in FND offers novel insights into the disorder’s neurobiology, with implications for therapeutic interventions to restore energy...
  4. Sean

    Crowdfunding for David Tuller starts October 1st 2024

    I have not got many emails from them, mostly just ones thanking me for a donation, best I can recall. But I am still getting the glossy paper mail stuff, despite writing to them a while back and asking them not to send them, which they acknowledged and said they would stop doing. And they did...
  5. Sean

    United Kingdom News (including UK wide, England, NI and Wales - see separate thread for news from Scotland)

    While I am generally in favour of locally managed service delivery, there still needs to be some broader national oversight to maintain standards and ensure that no local organisation goes too far off the rails.
  6. Sean

    Review Advocating the role of trained immunity in the pathogenesis of ME/CFS; a mini review, 2025, Humer et al

    I am fairly confident that when we do understand ME/CFS properly we are going to find that, for many patients at least, it has a prodromal phase, possibly quite a long one in some cases, up to decades, before it develops into the full blown syndrome. Also that the prodromal phase is going to...
  7. Sean

    2025: The 2019/24 Cochrane Larun review Exercise Therapy for CFS - including IAG, campaign, petition, comments and articles

    Cochrane are barely even pretending, are they. Can Cochrane be sued over this (for negligence and harm, maybe misleading advertising as the definitive authoritative source of clinical reviews)? Particularly in the UK.
  8. Sean

    "Shame, Psychology and ME": slides for presentation by Cheston, Richard; Cheston, Katharine

    Another victim of Prof Crawley's glorious career. :grumpy:
  9. Sean

    Review Pulmonary Rehabilitation for individuals with persistent symptoms following COVID-19 2024 Daynes et al

    a prevalence of at least one symptom of PEM WTF does that even mean? o_O
  10. Sean

    UK: All Party Parliamentary Group (APPG) on ME news, 2020 onward

    However, this is just not happening and very little progress has been made since publication of the new NICE guideline of ME/CFS in October 2021 – apart from the removal of graded exercise treatment from these services. Well, since the removal of the term 'graded exercise therapy' and the...
  11. Sean

    UK House of Lords/ House of Commons - relevant people and questions

    These services offer physical, cognitive, and psychological assessment, and, where appropriate, refer patients onto existing services for treatment and rehabilitation. SOS Same Old Shit.
  12. Sean

    News from the USA, United States of America

    "Do we have a single answer? Not as of yet, and most likely, perhaps we'll have more than one answer," he said. FFS, just say 'we don't know, we don't have any good answers at this stage', and leave it at that. Stop prejudicing the process when it has barely got started.
  13. Sean

    News from Scandinavia

    Leaving aside that this is a blatant insulting lie, even if it was true the question then becomes why, which leads to asking how the psychosomatic crowd have managed to become so dominant that they can block any research into alternative explanations. And answers to that that might be more than...
  14. Sean

    Psycho-gastroenterological profile of an Italian population of children with disorders of gut-brain interaction: A case-control study 2025 Giorgio+

    Four of the 8 significant results tell us nothing about causal directions (lower quality of life, more medical examinations, rising health care costs, and higher pain scores). They could all be the consequences of undiagnosed or untreated physiopathology. One (higher prevalence of early life...
  15. Sean

    Protocol Effects of an app-based physical training for long- and post-COVID treatment A PILOT study, 2025, Krieg+

    a gradual, individualised approach to physical activity. Straight from the BPS bible. They have learned nothing, and have no intention of doing so.
  16. Sean

    Review Effectiveness and cost-effectiveness of non-pharmacological interventions for functional somatic disorders: Systematic review... 2025 Boluda-Verdú+

    So, 74% of the studies are utter shit, 18% are shit, and less than 8% achieve a bare pass mark. This is beyond pathetic. It is a profound and deeply entrenched systemic failure of the peer-review system in this area of medicine.
  17. Sean

    Opinion mTORC1 syndrome (TorS): unifying paradigm for PASC, ME/CFS and PAIS, 2025, Bar-Tana

    That Which Does Not Kill Us Makes Us Stronger Nonsense, certainly in this context. It is more likely to leave one in a weaker state.
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