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  1. forestglip

    A natural experiment on the effect of herpes zoster vaccination on dementia, 2025, Eyting et al

    If eligibility for school was the reason for having more or less dementia, then you'd expect to see the same effect in other years, right? Instead of splitting the groups by being born before or after September 2, 1933, what if you split groups by being born before or after September 2, 1932...
  2. forestglip

    A natural experiment on the effect of herpes zoster vaccination on dementia, 2025, Eyting et al

    That's the thing. Selection bias doesn't really matter here. Simple way to imagine it: there's a room of people. They all randomly decided to wear a red or blue shirt that morning (akin to being born before or after the cutoff date in the actual study). Someone walks in and says "people...
  3. forestglip

    A natural experiment on the effect of herpes zoster vaccination on dementia, 2025, Eyting et al

    Are you referring to the new study linked in another thread? It's basically the same methodology as this thread's study, but instead of looking at dementia diagnoses, they looked at two other metrics: diagnosis of mild cognitive impairment and death from dementia. So something like a...
  4. forestglip

    The effect of shingles vaccination at different stages of the dementia disease course, 2025, Min Xie et al

    Thread for previous studies on this topic: Causal evidence that herpes zoster vaccination prevents a proportion of dementia cases, 2023, Markus Eyting
  5. forestglip

    A natural experiment on the effect of herpes zoster vaccination on dementia, 2025, Eyting et al

    See thread for new study from the Wales natural experiment study group: The effect of shingles vaccination at different stages of the dementia disease course, 2025, Min Xie et al
  6. forestglip

    United Kingdom: Teenager Ella Copley's experience with severe ME/CFS

    Note that a memorial thread has been set up for Ella: Ella Copley For general discussion of the Leeds service, see this thread: United Kingdom: Leeds and York Partnership - CFS centre
  7. forestglip

    Charity “Donation Matching”

    Also OMF, but only for a few more hours: https://www.s4me.info/threads/open-medicine-foundation-omf-fundraising.11837/post-658208
  8. forestglip

    Open Medicine Foundation (OMF) fundraising

    From an email: "Right now, there are only 48 HOURS LEFT to make your gift count even more. During our annual Triple Giving November campaign, all donations are tripled—up to $1 million—through December 2. This is a unique opportunity to multiply your impact and help accelerate research that...
  9. forestglip

    Trial Report Solriamfetol improves daily fatigue symptoms in adults with [ME/CFS] after 8 weeks of treatment, 2025, Young et al

    It says: A person named Harry Lei on the first site. The second link doesn't work, but I found this page for a Harry Lei in that organization, and the photo looks like the person on the Github page. I think it's a real person. Maybe they use AI to write lots of replies.
  10. forestglip

    Trial Report Solriamfetol improves daily fatigue symptoms in adults with [ME/CFS] after 8 weeks of treatment, 2025, Young et al

    A webpage for the above person: https://zlei2269.github.io/ Authors of another paper replying that a comment from Zhihao Lei basically doesn't make sense: https://www.europeanurology.com/article/S0302-2838(25)04679-2/abstract Edit: fixed link
  11. forestglip

    Paul Garner on Long Covid and ME/CFS - BMJ articles and other media.

    Unfortunately, that's the kind of evidence that's needed for a medical treatment. You keep saying this, but it's not evidence. It's just a person making an incredible claim. Anyone can come on the forum and say that they know of large numbers of people cured by a treatment. Even if you're...
  12. forestglip

    Paul Garner on Long Covid and ME/CFS - BMJ articles and other media.

    It just doesn't seem plausible to me that a treatment that works so well would not have strong published evidence by now. Have not similar things been touted as a treatment for decades? Where are the trials showing these remarkable results? Or is it that they only just recently come up with the...
  13. forestglip

    Vitamin D intake and multiple sclerosis risk in the Norwegian Mother, Father and Child cohort, 2025, Kapali et al.

    I think it's meant to double check that it's really vitamin D. They saw the association when combined, but weren't really sure if it might be only due to nutritional vitamin D or only due to supplemental D. If the association holds no matter what the source, that adds some confidence that it's...
  14. forestglip

    A general thread on the PACE trial!

    Some posts about Peter White have been moved to the dedicated thread: Professor Peter White
  15. forestglip

    Who is Simon Wessely?

    I haven't, but just adding a link here for easy access: https://redcircle.com/shows/00c09c2d-fedd-4eee-a9ec-262c89ba4d7a/ep/20165673-2a37-4f63-ab01-03bfa0f358b5 The part of the description that says what the episode is about:
  16. forestglip

    Altered brain tissue microstructure and neurochemical profiles in long COVID and recovered COVID-19 individuals: A multimodal MRI study, 2025,Thapali+

    Altered brain tissue microstructure and neurochemical profiles in long COVID and recovered COVID-19 individuals: A multimodal MRI study [Line breaks added] Background Diverse neurological symptoms are experienced by long COVID and COVID-19 recovered individuals. However, the long-term...
  17. forestglip

    T cell-driven sustained inflammation and immune dysregulation mimicking immunosenescence for up to three years post-COVID-19, 2025, Zheng et al

    T cell-driven sustained inflammation and immune dysregulation mimicking immunosenescence for up to three years post-COVID-19 [Line breaks added] Abstract Long COVID has emerged as a major global health concern, yet the long-term trajectory of immune recovery and its contribution to...
  18. forestglip

    Extracellular vesicles from [LC] patients promote RUNX2-mediated cellular stress via dysregulated miR-204 and p53 pathway activation, 2025, Dalle+

    Extracellular vesicles from long COVID patients promote RUNX2-mediated cellular stress via dysregulated miR-204 and p53 pathway activation [Line breaks added] Background: Subjects with Long COVID, also known as post-acute sequelae of SARS-CoV-2 infection (PASC)...
  19. forestglip

    Does the pathology of ME/CFS include brain damage?

    Maybe I'm misunderstanding. Do you mean ~50% of the 17 participants in the study were misdiagnosed by the investigators? I don't recall anything in the paper suggesting that.
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