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This is based on a meta-analysis of different studies, right? So I don't think it should match exactly. Anyway, that plot shows the output of the MAGMA gene-based analysis, not the main analysis DecodeME did that turned up all the candidate genes like RABGAP1L and CA10. In theory, it should...

Couple things previously said:

Discussion about an FND study and FND prevalence was moved to: Functional Neurological Disorder (FND) - articles, social media and discussion

Oh yeah, about this very claim/study: https://trialbyerror.org/2024/02/09/finally-our-letter-on-inflated-claims-of-fnd-prevalence-is-published/ Previously discussed...

It seems to be a common claim. Two examples: Functional Neurological Disorder: Historical Trends and Urgent Directions, 2023, Journal of Neurology Research (Link) Seminars in General Adult Psychiatry, p.369, 2024 (Link) Of the studies I looked at, they all seem to cite the same study...

Sorry, no, I can only see the abstract that was copied.

Investigating the Eye as a Biomarker of Gulf War Illness: Sphingolipid and Eicosanoid Composition in Tears and Plasma [Line breaks added] Abstract Gulf War Illness (GWI) is a chronic multi-symptom condition affecting veterans of the 1990–1991 Gulf War, with ocular discomfort increasingly...

Exaggerated IFN-I Response in Long COVID PBMCs Following Exposure to Viral Mimics Purpose Long COVID (LC) is a long-term debilitating disease of which the exact pathophysiology is unknown. A dysregulated immune response resulting in hyperresponsive immune cells is hypothesized as a key...

Merged posts ------- Long COVID vs. functional neurological disorder: Punching down Shelley Dawson Chapter from book Clashing Vulnerabilities, Disability and Conflict [Line breaks added] Abstract Shelley Dawson’s chapter documents a situation where clashing vulnerabilities are not only not...

One option is using a hypergeometric test to check how likely it is to have as large of an overlap as you got by chance. Described here with a built-in calculator: https://statisticsbyjim.com/probability/hypergeometric-distribution/ (Though the calculator doesn't seem to work when the sample...

Ivabradine as a treatment for postural orthostatic tachycardia syndrome: A systematic review Abstract Ivabradine is one of several off-label treatments for patients with postural orthostatic tachycardia syndrome (POTS). We conducted a systematic review of the literature to identify studies...

"Thanks to the Long COVID community, eligibility screening for LoCITT-T is now closed, 41 days after it oopened. We'll share more about what's ahead on 12/17 at 2:30 eastern / 11:30 pacific. https://scrippsresearch.zoom.us/webinar/register/WN_o1XdvBpcRwOmEj3Su_Ge6A" Julia MV on Bluesky

Looking at the list above, I do wonder about matching findings by chance. How many genes did your program identify, and how many genes did the latest PrecisionLife study identify? Didn't the latter report a few hundred or a few thousand genes? Seems to be an opportunity for a few genes to...

They said this: I'm looking at those tables and figures, but I can't see any reasons for withdrawals. Doesn't seem to be elsewhere in the supplement either. The protocol (Supplement 1) says:

Some posts discussing charity governance structure have been moved to United Kingdom: ME Association governance issues Please keep this thread for discussion of the reseach project.

Relevant tags with previous papers by this group and others: TRPM3, TRPM

Did different people write the Results and Conclusion of the abstract?

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): diagnosis and management [Line breaks added] Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) has garnered substantial scientific and clinical interest, due to its rising global prevalence and significant...

Wired: 'Scientists Thought Parkinson’s Was in Our Genes. It Might Be in the Water' Human Genome Project Trichlorethylene (TCE) Human Exposome Project Link to Human Exposome Project

A post about the Rosetta Stone study was moved to a dedicated thread: Rosetta Stone Study: £1.1m awarded to investigate links between ME/CFS and Long Covid