Exaggerated IFN-I Response in Long COVID PBMCs Following Exposure to Viral Mimics
Purpose
Long COVID (LC) is a long-term debilitating disease of which the exact pathophysiology is unknown. A dysregulated immune response resulting in hyperresponsive immune cells is hypothesized as a key...
Merged posts
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Long COVID vs. functional neurological disorder: Punching down
Shelley Dawson
Chapter from book Clashing Vulnerabilities, Disability and Conflict
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Abstract
Shelley Dawson’s chapter documents a situation where clashing vulnerabilities are not only not...
One option is using a hypergeometric test to check how likely it is to have as large of an overlap as you got by chance. Described here with a built-in calculator: https://statisticsbyjim.com/probability/hypergeometric-distribution/ (Though the calculator doesn't seem to work when the sample...
Ivabradine as a treatment for postural orthostatic tachycardia syndrome: A systematic review
Abstract
Ivabradine is one of several off-label treatments for patients with postural orthostatic tachycardia syndrome (POTS). We conducted a systematic review of the literature to identify studies...
"Thanks to the Long COVID community, eligibility screening for LoCITT-T is now closed, 41 days after it oopened.
We'll share more about what's ahead on 12/17 at 2:30 eastern / 11:30 pacific.
https://scrippsresearch.zoom.us/webinar/register/WN_o1XdvBpcRwOmEj3Su_Ge6A"
Julia MV on Bluesky
Looking at the list above, I do wonder about matching findings by chance. How many genes did your program identify, and how many genes did the latest PrecisionLife study identify? Didn't the latter report a few hundred or a few thousand genes? Seems to be an opportunity for a few genes to...
They said this:
I'm looking at those tables and figures, but I can't see any reasons for withdrawals. Doesn't seem to be elsewhere in the supplement either.
The protocol (Supplement 1) says:
Some posts discussing charity governance structure have been moved to United Kingdom: ME Association governance issues
Please keep this thread for discussion of the reseach project.
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): diagnosis and management
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Background
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) has garnered substantial scientific and clinical interest, due to its rising global prevalence and significant...
Wired: 'Scientists Thought Parkinson’s Was in Our Genes. It Might Be in the Water'
Human Genome Project
Trichlorethylene (TCE)
Human Exposome Project
Link to Human Exposome Project
A post about the Rosetta Stone study was moved to a dedicated thread: Rosetta Stone Study: £1.1m awarded to investigate links between ME/CFS and Long Covid
Posts about Rosetta Stone study were moved to a dedicated thread: Rosetta Stone Study: £1.1m awarded to investigate links between ME/CFS and Long Covid
Virtual Pet–Assisted Therapy to Alleviate Symptoms of Long COVID: A Prospective Pilot Interventional Study
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Background: Post–COVID-19 condition (long COVID) is characterized by persistent symptoms following acute infection. Given the limited efficacy of pharmacologic...
Reply to: Methodological Issues in Taquet et al.'s analysis preclude any conclusions regarding AS01 adjuvant's specific role in dementia prevention
Taquet, Maxime; Todd, John A.; Harrison, Paul J.
Abstract
In our study, we compared the risk of dementia between matched cohorts of patients who...
Discussion of on a stellate ganglion block trial has been moved to its own thread: Stellate Ganglion Block for the Treatment of COVID-19−Induced Parosmia, 2025, Farrell et al
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