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  1. forestglip

    Peripheral Levels of Selected Biomarkers in Patients with Post-Sarcoidosis Chronic Fatigue Syndrome, 2025, Małujło-Balcerska et al

    Peripheral Levels of Selected Biomarkers in Patients with Post-Sarcoidosis Chronic Fatigue Syndrome [Line breaks added] Introduction Chronic fatigue syndrome (CFS) is characterized by persistent fatigue and multiple symptoms such as cognitive impairment and muscle pain, often linked to...
  2. forestglip

    Effect of subcutaneous lidocaine–hydroxypropyl-β-cyclodextrin (HP-β-CD) on quality of life in patients with post-COVID condition…, 2025, Oostwouder+

    Subjective outcomes and no placebo. Speculation on why it would work: On why they think these don't resemble placebo effects: Primary outcomes: Secondary outcomes were individual symptoms. The ones furthest to the left had the largest improvements: Edit: Removed misinterpretation...
  3. forestglip

    News from The Netherlands

    The Sick Times: '“Not Recovered” protest for Long COVID, ME, and related diseases takes over The Hague' "Thousands of people took part online and in person for the hybrid protest calling for recognition of people with these diseases, better care, appropriate policy, and long term funding of...
  4. forestglip

    Preprint Identification of Novel Reproducible Combinatorial Genetic Risk Factors for [ME] in [DecodeME Cohort] and Commonalities with [LC], 2025, Sardell+

    Is it this: I think in figure 1 it says the test cohort has 3,579 cases and 113,735 controls.
  5. forestglip

    A natural experiment on the effect of herpes zoster vaccination on dementia, 2025, Eyting et al

    I think she might have missed that sensitivity check in the paper. Here's someone asking her if the peer reviewed version of the study checking other years allays her concerns (her post was about the preprint). Response: The same sensitivity check the person asked about was in the preprint...
  6. forestglip

    A natural experiment on the effect of herpes zoster vaccination on dementia, 2025, Eyting et al

    If eligibility for school was the reason for having more or less dementia, then you'd expect to see the same effect in other years, right? Instead of splitting the groups by being born before or after September 2, 1933, what if you split groups by being born before or after September 2, 1932...
  7. forestglip

    A natural experiment on the effect of herpes zoster vaccination on dementia, 2025, Eyting et al

    That's the thing. Selection bias doesn't really matter here. Simple way to imagine it: there's a room of people. They all randomly decided to wear a red or blue shirt that morning (akin to being born before or after the cutoff date in the actual study). Someone walks in and says "people...
  8. forestglip

    A natural experiment on the effect of herpes zoster vaccination on dementia, 2025, Eyting et al

    Are you referring to the new study linked in another thread? It's basically the same methodology as this thread's study, but instead of looking at dementia diagnoses, they looked at two other metrics: diagnosis of mild cognitive impairment and death from dementia. So something like a...
  9. forestglip

    The effect of shingles vaccination at different stages of the dementia disease course, 2025, Min Xie et al

    Thread for previous studies on this topic: Causal evidence that herpes zoster vaccination prevents a proportion of dementia cases, 2023, Markus Eyting
  10. forestglip

    A natural experiment on the effect of herpes zoster vaccination on dementia, 2025, Eyting et al

    See thread for new study from the Wales natural experiment study group: The effect of shingles vaccination at different stages of the dementia disease course, 2025, Min Xie et al
  11. forestglip

    United Kingdom: Teenager Ella Copley's experience with severe ME/CFS

    Note that a memorial thread has been set up for Ella: Ella Copley For general discussion of the Leeds service, see this thread: United Kingdom: Leeds and York Partnership - CFS centre
  12. forestglip

    Charity “Donation Matching”

    Also OMF, but only for a few more hours: https://www.s4me.info/threads/open-medicine-foundation-omf-fundraising.11837/post-658208
  13. forestglip

    Open Medicine Foundation (OMF) fundraising

    From an email: "Right now, there are only 48 HOURS LEFT to make your gift count even more. During our annual Triple Giving November campaign, all donations are tripled—up to $1 million—through December 2. This is a unique opportunity to multiply your impact and help accelerate research that...
  14. forestglip

    Trial Report Solriamfetol improves daily fatigue symptoms in adults with [ME/CFS] after 8 weeks of treatment, 2025, Young et al

    It says: A person named Harry Lei on the first site. The second link doesn't work, but I found this page for a Harry Lei in that organization, and the photo looks like the person on the Github page. I think it's a real person. Maybe they use AI to write lots of replies.
  15. forestglip

    Trial Report Solriamfetol improves daily fatigue symptoms in adults with [ME/CFS] after 8 weeks of treatment, 2025, Young et al

    A webpage for the above person: https://zlei2269.github.io/ Authors of another paper replying that a comment from Zhihao Lei basically doesn't make sense: https://www.europeanurology.com/article/S0302-2838(25)04679-2/abstract Edit: fixed link
  16. forestglip

    Paul Garner on Long Covid and ME/CFS - BMJ articles and other media.

    Unfortunately, that's the kind of evidence that's needed for a medical treatment. You keep saying this, but it's not evidence. It's just a person making an incredible claim. Anyone can come on the forum and say that they know of large numbers of people cured by a treatment. Even if you're...
  17. forestglip

    Paul Garner on Long Covid and ME/CFS - BMJ articles and other media.

    It just doesn't seem plausible to me that a treatment that works so well would not have strong published evidence by now. Have not similar things been touted as a treatment for decades? Where are the trials showing these remarkable results? Or is it that they only just recently come up with the...
  18. forestglip

    Vitamin D intake and multiple sclerosis risk in the Norwegian Mother, Father and Child cohort, 2025, Kapali et al.

    I think it's meant to double check that it's really vitamin D. They saw the association when combined, but weren't really sure if it might be only due to nutritional vitamin D or only due to supplemental D. If the association holds no matter what the source, that adds some confidence that it's...
  19. forestglip

    A general thread on the PACE trial!

    Some posts about Peter White have been moved to the dedicated thread: Professor Peter White
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