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  1. Sid

    A general thread on the PACE trial!

    Coyne’s article rings true. The peer review system is crazy and must go. I’ve experienced many weird, incorrect reviews over the years. Not ad hominem abusive like what he describes at the BMJ (which is a huge cesspit) but just people not reading your article or saying wrong things and the...
  2. Sid

    Contesting the psychiatric framing of ME/CFS, 2017, Spandler and Allen

    That’s the thing. The psych framing presupposes that the patient hasn’t tried the blindingly obvious solution first which is to exercise your way out of it. They are saying we are that stupid and insane that we just took to bed and never tried to take any action to get out of it.
  3. Sid

    Anomalies in the review process and interpretation of the evidence in the NICE guideline for (CFS & ME), 2023, White et al

    The whole negotiation thing implies that the patient is refusing to do more activity for no reason and that the job of the therapist is to coax them into doing the right thing by negotiating little increments each week. It’s very insulting and wrong.
  4. Sid

    The multi-generational familial aggregation of interstitial cystitis, other chronic nociplastic pain disorders, depression, & panic disorder 2023 Fyer

    Not surprised to see this link. IC is one of the symptoms I’ve struggled with as part of my ME/CFS.
  5. Sid

    Professor Gerd Kvale on Long Covid

    You’re doing too little AND too much.
  6. Sid

    Reddit - Interesting posts on Reddit, including what some doctors say about ME/CFS

    The losses far exceed the gains as far as I can see. Losses include moronic pimply junior doctors feeling entitled to speculate about your mental state and motivations.
  7. Sid

    Anomalies in the review process and interpretation of the evidence in the NICE guideline for (CFS & ME), 2023, White et al

    FND is just the name neurologists give to ME/CFS (and other unexplained symptoms). So it’s not surprising at all that FND people are involved in this.
  8. Sid

    Neuro appointment soon.... Avoiding an FND diagnosis

    Yes, or losing credibility. I mean, this stuff is so prevalent now.
  9. Sid

    Neuro appointment soon.... Avoiding an FND diagnosis

    I’m not in the UK but I heard a psychiatry colleague mention FND and cite Stone’s incorrect prevalence estimate in neurology consults. I had never EVER heard anyone use that phrase offline in my life previously so the cancer is definitely spreading far and wide. I almost replied “ACTUALLY...
  10. Sid

    Functional Neurological Disorder (FND) - articles, social media and discussion

    I’m surprised he’s able to get away with having this website up and advertising his nonsense directly to patients. If this were a medicinal product not CBT he would have been shut down by the regulator already. There is no evidence for his claims. The CODES trial definitively showed that CBT...
  11. Sid

    Suramin as a possible treatment for Autism, ME CFS and Long Covid

    Also, it looks like one patient in this small study got status epilepticus in the 20 mg group. Not saying this is causally related but it should be noted. https://www.europeanpharmaceuticalreview.com/news/164740/iv-suramin-may-be-a-promising-autism-treatment-shows-phase-ii-study/
  12. Sid

    Suramin as a possible treatment for Autism, ME CFS and Long Covid

    So it seems that the Phase II trial in South Africa did not replicate Naviaux’s original finding of 20 mg being more effective than placebo. He had 5 patients per arm in the original trial if I recall. In this new trial, 10 mg appeared to be more effective in that it seemed to separate from...
  13. Sid

    One-session treatment compared with multisession CBT in children aged 7 16 years with specific phobias: the ASPECT non-inferiority RCT, 2023, Wright

    Treatment of simple phobia is the only area where I would concede that efficacy of CBT over doing nothing has been demonstrated. However, this is the easiest psychiatric disorder to treat, low hanging fruit. Evidence is a lot muddier for more complex anxiety disorders like panic with...
  14. Sid

    Article: Science: Is exercise actually good for the brain?

    Good to see this sort of material out there. The exercise lobby is so strong despite no evidence of benefit for weight loss or other outcomes.
  15. Sid

    Pitching to Panorama: Efforts to commission a documentary on NICE guideline, bad science (PACE etc), and patient harm

    Netflix is hit and miss and has much lower credibility than BBC but it’s better than nothing. Netflix recently made a documentary about CRPS, another contested illness considered functional by some, and it was heavily biased in favour of the family and against the mainstream physicians involved...
  16. Sid

    Pitching to Panorama: Efforts to commission a documentary on NICE guideline, bad science (PACE etc), and patient harm

    Interesting background. I didn't know that BBC commissioned a statistician to review PACE. Without knowing more details about the statistician's report, it's difficult to judge its scope or accuracy. As someone who was closely involved in the statistical reanalysis of PACE FOIA dataset, I can...
  17. Sid

    First major survey of doctors with Long Covid reveals debilitating impact on health, life and work, 2023, BMA media team

    It’s quite funny actually seeing people who abused and derided us all their lives get felled by basically the same condition.
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