Search results

A few years back I tried to get an understanding years of my own blood tests that indicated NK cell count being extremely low and having some other anomalous immune results from blood tests. I ended up consulting with the head of the immunology department at a University research Hospital. he...

@ryanc97, how confident are you that your NK cell tests are accurate?

I recently watched this video. It features some researchers at the AI company, “Anthropic”, discussing what they know and don’t know and how they approach the problem of how their AI models actually work. They still don’t understand it very well. At one point I thought, “they need to talk to...

I have another basic question.: Now that you have the data, how much effort is involved in doing an GWAS association test? Are you considering doing other GWAS association tests?

The symptom is specifically "muscle pain", not any other type or location.. of course, what is muscle pain?

was anyone else besides me surprised that 86.1% of the cohort reported "muscle pain"? many years of following ME/CFS forums, webinars, conferences led me to believe the number would be much lower. I’m not saying this number is good or bad or inaccurate, just that it surprised me.

As I posted on another thread, in reference to this statement, Please discuss the significance of this GWAS result, keeping in mind that "not reporting an infectious onset" only means they patient does not remember having symptoms of an infection, but the infection could still be occuring…

So, what does this GWAS report indicate for those people who did not report an infection as a trigger?

I am reading the Preprint. So what does this sentence in the Preprint tell us?

I was in the Naviaux metabolic validation study sponsored by the OMF. Dr Gordon conducted a qualifiying interview with me for entrance into this study (which was never published). I was not impressed. I was rather shocked at the lackadaisical nature of the interview.

I have always harbored the same thoughts about patient selection. Do you think there’s a patient continuum from fibromyalgia to ME/CFS or is it too hard to tell at this point in time?

Jonathan, I am curious, what are the better/best ways to "pin this down"?

This is disapointing… …"This implies that experience of trauma and distress might elicit a specific immune-biological response in genetically or otherwise (eg, past infection, toxicity, trauma) vulnerable individuals, which includes the production of harmful noninflammatory autoantibodies." …...

wiggle, Yeah, when I watched the video I was wondering what were the discussions between Dr. Systrom and Dr. Wurst, etc... ... one of those times it's exciting to be a scientist.

and this one by Dr Wurst on skeletal muscle alterations:

I also appreciated this update on Dr. Systrom's pyridostigmine and low dose Natrexone study.

Thanks again!! I watched the first video - Anouk Slaghekke. That is an impressive presentation. It appears long covid and ME/CFS data really match each other in this measurement. I wonder what that implies… It is also a pleasure to see someone so excited to be presenting. after watching the...

@SNT Gatchaman, thank you for posting this video. Are there any others from that conference that you recommend?

Wiggle, I also find this from Cornell. it references a paper that describes a methodology…. https://neuroimmune.cornell.edu/research/differential-gene-expression-in-muscle-cells/

Sasha, same for me. I do a search for "Jonathan Edwards" and then tap on the "since 2025" option and the paper pops up. hope this helps.