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  1. Arnie Pye

    Whole genome sequencing - how it works on the NHS

    Link : https://edition.cnn.com/2023/03/19/health/newborn-genomes-programme-uk-genomics-scn-spc-intl/index.html?utm_source=pocket-newtab-global-en-GB There is a very glaring error in the article. Someone with an absent or under-developed thyroid gland would have congenital hypothyroidism, not...
  2. Arnie Pye

    Is severe tiredness 'chronic fatigue' or something else? : Story by Dr Martin Scurr

    It's unfortunate that the daughter's traumatic birth isn't described. Did she have a prolonged birth which resulted in permanent damage to bladder/bowel? A stillbirth? Did she have a catastrophic bleed? Was she given a caesarean and have her bowel punctured and develop sepsis, and/or lose her...
  3. Arnie Pye

    High Perceived Stress and Low Self-Efficacy are Associated with Functional Somatic Disorders: The DanFunD Study, 2023, Fink et al

    I wonder what these authors think of patients who are stressed for some "acceptable" reason e.g. the death of a loved one, patient's house burns down and they lose everything, severe accident of some kind, loss of a job with the prospect of losing a home and/or hunger to come, being a soldier...
  4. Arnie Pye

    Endoscopy - sedation ?

    I was given an upper endoscopy with sedation. The sedative drug was one of the ones that causes amnesia. Under the circumstances it is not surprising I have no memory of the procedure itself nor how cooperative I was. It was one of the earliest date-rape drugs - Rohypnol. I was given a cup of...
  5. Arnie Pye

    Lost Time

    A really good description. Hopefully I'll remember "empty time" and "standby mode" as useful descriptions. One of the reasons that I gave up work was because there were parts of the year when I had to do a series of days where I worked all day (admittedly with a late start) and couldn't leave...
  6. Arnie Pye

    FNDs after COVID-19 and SARS-CoV-2 vaccines: a national multicentre observational study 2023 Alonso-Canovas et al

    Galen's idea that the body ran on "four humours" i.e. yellow bile, black bile, blood, and phlegm, lasted for around 1000 - 1500 years. How long is FND going to last?
  7. Arnie Pye

    Trisha Greenhalgh on ME/CFS and Long Covid

    That used to work for me, but for some unknown reason it doesn't any more.
  8. Arnie Pye

    Trisha Greenhalgh on ME/CFS and Long Covid

    Anyone who wants to read what TG says without being unblocked can just log out of Twitter and then read what she has to say. You will probably be prompted to make an account and log in, but if you close the prompt box you should be able to continue. Alternatively follow the prompts until you are...
  9. Arnie Pye

    SMART Pharmacists Serving the New Needs of the Post-COVID Patients, Leaving No-One Behind 2023 Šipetić et al

    In the last few years I have gone to my GP surgery and been treated by GPs, nurses, pharmacists, and paramedics. In each case they were prescribing things for me. How can I tell when the person prescribing for me is acting outside their competence level, if they aren't a GP? Edit : This is a...
  10. Arnie Pye

    US - The Sleepy Girl Guide to Social Security Disability

    Thanks for the info. I thought it might be something like that. I have to say, I hate the name, no matter how good the site is, but then my opinion is of zero relevance in this. :D
  11. Arnie Pye

    US - The Sleepy Girl Guide to Social Security Disability

    I haven't read the links, but that title referring to "The Sleepy Girl Guide" is incredibly condescending. Would anyone ever describe anything medical as "The Sleepy Boy ...". The medical profession routinely infantilises women, and this kind of sexist title needs to stop. I wouldn't have minded...
  12. Arnie Pye

    Trial Report Possible Markers For Myalgic Encephalomyelitis / CFS Developed In Long Covid: Utility Of Serum Ferritin And Insulin-like Growth Factor-I,2023,Yamamoto

    Although labs aren't moving quickly on this in the UK, NICE has brought out guidelines for iron deficiency anaemia (last revised Nov 2021) that mention ferritin and it raised the lowest part of the range from 13 to 30 mcg/L. The standard range for women for many years was 13 - 150 mcg/L, and in...
  13. Arnie Pye

    Traumatic brain injury - similarities with and differences to ME/CFS, including PEM

    Has anyone ever had all their pituitary and hypothalamus hormones tested (there are quite a lot of them) after severe illness or injury affecting the brain? According to this link : https://en.wikipedia.org/wiki/List_of_human_hormones (I'm dubious about the following numbers because I wasn't...
  14. Arnie Pye

    Cushing’s Disease Presenting with Functional Neurological (Conversion) Disorder 2023 Ashrafzadeh et al

    I hope the hospitals and doctors involved in this man's "care" and who ignored the serious symptoms and diagnoses he had are sued for a huge amount of money for malpractice and negligence
  15. Arnie Pye

    Cushing’s Disease Presenting with Functional Neurological (Conversion) Disorder 2023 Ashrafzadeh et al

    I get the impression that the authors looked up a list of symptoms for Cushing's on wikipedia then declared any other symptoms the patient suffered from as FND. What would be more useful and less sadistic is for the patient to be treated for CS, get their thyroid checked, and get any nutrient...
  16. Arnie Pye

    Independent advisory group for the full update of the Cochrane review on exercise therapy and ME/CFS (2020), led by Hilda Bastian

    Given what happened to postmasters and postmistresses in the UK because of accountancy software with bugs in it I think the prospect is terrifying. https://en.wikipedia.org/wiki/British_Post_Office_scandal
  17. Arnie Pye

    Intensive Short-Term Dynamic Psychotherapy associated with healthcare reductions in patients with functional seizures 2023 Malda-Castillo et al

    Perhaps ISTDP reduces health costs because patients realise that doctors have nothing to offer them so they stop using the health system.
  18. Arnie Pye

    Comparison of mental health symptoms before & during the covid-19 pandemic: evidence from a systematic review & meta-analysis of 134 cohorts 2023 Sun

    Does anyone have a list of what officially constitutes "mental health", anxiety or depression symptoms? If I had a pain in my left big toe would that be classed as a depression or anxiety symptom if I was negative for gout and/or ingrowing toenails? (If I could even get a test for gout done.)
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