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    Question concerning XMRV

    Thanks @Jonathan Edwards . Our GP just shrugged their shoulders and did not think it worth any further investigation . It has always seemed unusual. We have a number of dots that havn' t been joined, and i think that may not be uncommon for ME: it is the sum of insults, in our case with...
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    Question concerning XMRV

    @Jonathan Edwards - how common is it to get shingles aged 9/10?
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    Michael Sharpe skewered by @JohntheJack on Twitter

    Statins share the same issues with raw data and data manipulation that we are all painfully familiar with. I' m not sure anyone could confidently make claims as to their efficacy. http://bjsm.bmj.com/content/early/2018/01/16/bjsports-2017-098497
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    Eosinophilic colitis caused by neuropathic agents in a patient with CFS (2018) Fragkos et al.

    I do wonder that If this person had not been in London ( assumption due to hospital details) and/ or If this was to happen in a couple of years time with IAPT roll out / MUS agenda/ IBD and SNOWMED codings Just how seriously this would have been investigated....
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    Michael Sharpe skewered by @JohntheJack on Twitter

    Sorry have not read the document ...
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    Michael Sharpe skewered by @JohntheJack on Twitter

    I have read the document, so apologies if this is covered. The impact of losing employment is perhaps more complex. Health may be impacted when the closure and redundancy is associated with a major employer and there is little opportunity for other employment - such was the case in the 1980s...
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    The ME Show

    Another great podcast @Gary Burgess . It was lovely to hear your voice @Trish, and to have those nuggets of experience. These are worth their weight in gold. Like you i hope biomedical research can make significant inroads for my daughter too.
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    The Challenges and Complexities of Thyroid Hormone Replacement (2010) Kansagra et al.

    My aunt had a partial.thyroidectomy in 1980. With ME her hormones were all over the place. She has been using temperature readings to titrate medication dosages and this seems to help stabilize things. Note adrenals are often overlooked and can create havoc - there dosn' t seem to be a "...
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    Hair and salivary cortisol in a cohort of women with chronic fatigue syndrome, 2018, Roerink et al

    I did not know of the pain / cortisol relationship. Neither did our endocrinologist it seems as he was stumped by low base cortisol reading but ok response on ACTH test. ..
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    Analysis of data from 500k individuals in UK Biobank shows an inherited component to ME/CFS (Ponting blog)

    23 and me dosn' t cover this ( checked my aunt' s data from earlier thus year)
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    Analysis of data from 500k individuals in UK Biobank shows an inherited component to ME/CFS (Ponting blog)

    The EDS thought did occur, could this be simpler and be indicative of a catabolic / inflammatory predisposition?
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    The Challenges and Complexities of Thyroid Hormone Replacement (2010) Kansagra et al.

    There are very long threads in the other place re thyroid The paper published earlier this year induced low T3 state, linking to Naviaux' s dauer state is interesting. There was a thread on it i think...
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    How to get 'Voices from the Shadows' viewed by more people

    I have not watched either, though i should. I do know that it has had effect when forwarded by Tymes Trust to doubting educational staff.
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    Michael Sharpe skewered by @JohntheJack on Twitter

    Iatrogenic damage to be done Comorbid treatable conditions to be disregarded Other illnesses to be written off without investigation ......
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