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I have never found the computer software-hardware metaphor useful for describing and understanding biological systems ('wetware'). Very misleading metaphor that should not be used.

'Degree of pyschosocial intervention for chronically ill patients correlates strongly with levels of irritation in those patients at the psychosocial interventions, says new study.' '"Clearly more psychosocial intervention is required", say leading psychosocial intervention experts, to...

I think Wessely called it a "thing of beauty".

Now they are just taking the piss. :grumpy:

No point in getting the data because they stuffed up the randomisation. Any further outcomes data would be meaningless.

A new government, looking for bricks to throw at their predecessors, could help there. One thing is for sure, nothing much will change for the next month. (For the benefit of non-Aussies, we have a national election on 18 May.)

Sharpe's tactic of blocking those who disagree, especially when they cite evidence, is going to backfire badly on him.

I think @dave30th is entitled to a right of reply. Reuters owes him that much at least. Kelland knew exactly what she was doing. It's a hit job, designed entirely to destroy an effective and legitimate critic.

If the results from all four methods hold up for bigger sample sizes, then we are cooking with gas. :nerd:

That works.

Thank you, Cort. :thumbup:

The hypocrisy of the BMJ is breathtaking, and more than a little disturbing. :grumpy:

I would be happier with one on the wrist and one on the ankle. But at least they are using them.

Bean counters will most likely be the ones who actually bring the axe down on this madness.

Liar. It did not assess methodology.

rhetorical juju :D

The cognitive-linguistic gymnastics these clowns will indulge in just to avoid simply saying 'I don't know', never ceases to amaze me.

Three independent teams, using three different methods, with the same result. Given the methodologies are sound (including statistical power), then this is looking like the best possibility so far for both a specific and unique (?) biomarker, and a leading research clue. :thumbup::)

Woo goo.

I strongly encourage Jerome Burne to read the full document linked to by Sharpe, and find out exactly what it really said about PACE and its methodology. Sharpe is relying on people not reading it in full, nor following up on the full context...