Search results

Would it have to also be in the muscle or could it be solely in the brain? DecodeME points strongly to the brain right? I guess that's harder to test?

The way I'm understanding this is that the 8 highlighted results are genomic loci / variants (SNPs). These point to a region in the DNA, not to one specific gene. These genomic loci are then named after the closest gene. Which is why they seem to appear as specifc genes. But it's not guaranteed...

Will be a long wednesday till 7pm though :nailbiting::emoji_smile:

Let's go!! :woot:

Agreed! I made a slight update to my comment which you might not have seen yet.

I don't know how common it is but (especially severe) PEM does make me feel very depressed. I don't struggle with depression at all outside of PEM. Then again it's somewhat similar to the depressed feeling I sometimes get when I'm very sick, so maybe it fits more with that theory.

Causes of symptoms and symptom persistence in long COVID and myalgic encephalomyelitis/chronic fatigue syndrome Anthony L. Komaroff, Robert Dantzer Abstract Debilitating symptoms for many years can follow acute COVID-19 (“long COVID”), myalgic encephalomyelitis/chronic fatigue syndrome...

This really reads as if they're just making shit up as they go along.

Great analogy!

Damnit you beat me by 4 minutes haha! :emoji_unamused:

Yeah that's a lot easier to say as a former health minister, rather than as a current one. Still, it's hopeful and exactly the kind of language I missed in the UK delivery plan.

They actually make some pretty accurate statements but then draw the complete wrong conclusions.

In the Netherlands they're trying to set up something like that (well, no public clinics, that's only for LC, see below, but they do work with private clinics). NMCB: ME/CFS Lines: Also for Long Covid: Post-COVID Network Netherlands: For Long Covid they did set up expert clinics in most...

I'm not against it I just think effects will be marginal. We know there's some drugs that slightly help people with symptoms. And small improvements are a big deal for people with ME/CFS. But I'm not convinced we need specalists just to prescribe beta blockers, sleep meds or LDN or whatever. I'm...

Now we're cooking! Honestly I really don't see the point in all the supposed ME/CFS "care" anyways. People just need to be diagnosed, get disability, home care (if necessary) and nutritional support in extreme cases. Trying to offer anything else just deludes doctors and public officials into...

OMF is already doing a trial on LDN. I wouldn't mind seeing a trial on LDA though. Daratumumab could also use some funding. Edit: to be clear though, I agree, we need leads first.

I woke up feeling irritated and this thread has grown that into full on anger lol.. :banghead: I wish someone could scream some sense into them. Like they say "oh we invested over £6.5m into research over the past 5 years and we're planning 2 new useless projects of around £2m". And we're...

The possibilities definitely seem endless. I mentioned in another thread that even doing too little seems to make me worse..

It was.. so I'm also not sure what they meant in relation to your comment.

I raised it earlier today: It obviously isn't part of the core pathophysiology. I was just musing about whether it could have some relevance in (permanent) detoriation and one's severity in general.