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I worry that we are providing medical advice here. Medical advice is not just recommending prescription medicines but any advice given in medical situation, including advice that might delay getting a medical opinion. Weight loss and diarrhoea for 8 weeks requires a medical diagnosis following...

It sounds as if you need medical advice. If you are acutely concerned that may mean accident and emergency. I assume you are in the UK and the GP system has really ceased to function for anything of serious importance.

Yes. Also if you cool the skin the hypothalamus may think it needs to increase metabolism and heat the core up further - including the brain.

How do you access this @Sasha?

No, not bad for science. Good that we all know what has been going on. Real science can cope with that. Bad science might be worried.

I think this is what we need to avoid. 'Regenerative medicine' is a phoney term banded about by people who want to get money for 'stem cell' research. I have involuntarily been part of the UCL 'regenerative medicine' consortium for about ten years and all I ever saw was politicos taking rhubarb...

They probably did have projects waiting. Research projects into brain tumours are easy to think of because you can grow the cells in the lab and study animal tumours and try out different drugs and so on. The problem with ME is that it is unclear what to do. Raising awareness amongst...

My impression is that although NICE may have made a bodge of selecting stakeholders for the initial meetings there were enough relevant people there to make the important points. From now on I suspect 'stakeholders' are not involved in the process, just the committee that gets formed...

Yes, that crossed my mind. For me it was bog standard advice from an old clinical researcher to a younger researcher who might not have any direct clinical background.

It seems not. https://jcoynester.wordpress.com/2017/04/13/why-i-am-formally-requesting-the-data-set-from-a-cochrane-review/ gives some idea. Larun is at the Norwegian Institute of Public Health.

Yes, that is what I was calling a 'paper'. This to me tells us nothing particularly important. I was responsible for diagnosing and treating heart attacks starting from 1974 as an intern and then as a registrar in A/E for about ten years. The range of symptoms given there was very familiar. The...

It says: Bayer actually started the ritual in the early 20th century in order to keep their pills in place. Powder pills would often break from moving around in the bottle and people weren't getting their proper dosage because they would try to piece them together. Medicine has come a long way...

Today's episode looked pretty messy too. It seems to have a John Le Carré feel in the sense that the good guys never quite get a chance even when you think they might. But there's two more episodes to go I gather...

Perhaps you are a bit modern too, Sasha. I think we called them aspirins because they came in a jar of 500 with cotton wool at the top. It may be that my father had filched them from the pharmacy at work but I think even Boots supplied bottles like that (brown ones) until they started worrying...

Is that because Chinese is written from right to left?

I realise we have to treat you Americans with sympathy, since things are going a bit awry in the Senate these days, but the English take aspirins, usually three to make 900mg. We don't take some penicillins or even paracetamols (which I think you refer to as acetaminophen) but these are a bit...

This is a very old story. Essentially it says 'a badly controlled study was done about ten years ago and because the result does not suit us we want to make sure we publish this fact, even if it has taken us ten years to get the paper accepted'. The point that you have to treat test and control...

I think what they will do is this. They will say these arguments are pretty similar (which they are): Hysteria is more common in women, so ME is hysteria. Medicine is sexist, so the lack of treatment of ME has been sexist. So the ME advocates are really just the same as the BPS advocates -...

I think Munafo has listened. And not shut the door. My impression is that he might have said more but that he also has to gauge what he says in public. A useful exchange.

You might want to see a psychotherapist about that. Preferably one not trained in psychology but who makes good home made lemonade and has some aspirins.