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  1. Jonathan Edwards

    Concerns about Cochrane

    Sometimes google translate seems to preserve the poetry!
  2. Jonathan Edwards

    LP coach on research, Lightning Process and ME (Norway)

    The problem is that they do not actually know what they mean by these words. They think the words must mean something and when they all say them together they convince each other of it, but they don't. Stupid people will go on behaving like this forever. And as we can see from the election of...
  3. Jonathan Edwards

    UK CMRC 2018 Conference held September 19 & 20 at Bristol

    £20 million is always available from MRC for ME but it only makes sense for them to offer it to someone if they can show they have a good idea to work on. If £20million was offered to anyone who came along we would immediately have someone snapping it up who had no idea what they are doing - we...
  4. Jonathan Edwards

    Brain glial activation in fibromyalgia – A multi-site positron emission tomography investigation (2018) Albrecht et al.

    Interesting. It looks a well planned study at first glance. The data are plausible and would be very significant if confirmed.
  5. Jonathan Edwards

    Trying Again. What First? D-Ribose? BCAA's?

    It is pretty easy because it is really quite hard to be short of basic requirements. If someone is short of vitamin C then to my mind the answer is to eat some fruit. You are obviously at liberty to do whatever you like but the idea that supplements are needed at all is as far as I know almost...
  6. Jonathan Edwards

    Concerns about Cochrane

    I think they are quite specifically failing to be specific and yes it is far worse. The only good thing I see hear is that their handling of the situation is so bad they will lose all credibility. Cochrane is busted I think.
  7. Jonathan Edwards

    Berkeley Wellness: When Medical Symptoms Are Dismissed as "All in Your Head" (David Tuller interviews Maya Dusenbery)

    Is there any reason to think that? Much of the time there seems to be no obvious reason to make a distinction but where there is a reason it is usually done. Risk estimates in cardiovascular disease take into account sex difference in all sorts of ways. I think it is pretty unusual to have an...
  8. Jonathan Edwards

    Concerns about Cochrane

    Maybe he cracks his finger joints during committees? It's laughable. Maybe the opposite of dis-rupt is co-rrupt?
  9. Jonathan Edwards

    Bristol - New Network - Prof Munafo

    Very nicely made point. To be frank his answer is wimpish and disingenuous. If he wants to change research culture he needs to get out there with a placard and get very mired in those debates. Edit: I see things have moved on. I am sure Graham and Sasha will find the perfect compromise without...
  10. Jonathan Edwards

    Trying Again. What First? D-Ribose? BCAA's?

    My guess is that people with ME in the UK probably spend about £50million on supplements a year. That is enough to run twenty five £10million five year grants simultaneously. We don't even have that number of research departments to give that sort of money to. So maybe it should be five...
  11. Jonathan Edwards

    Concerns about Cochrane

    Bastian ends with We have to increase our skills at detecting bias, error, and the signs of fear mongering – and remember that it’s dangerously easy to be led astray by someone else’s passionately held conviction. This sounds like an admission of naïvety to me. In my view it is actually quite...
  12. Jonathan Edwards

    Berkeley Wellness: When Medical Symptoms Are Dismissed as "All in Your Head" (David Tuller interviews Maya Dusenbery)

    I don't think that is plausible. Remember that in 1970 in the UK every unexplained death had an autopsy, which students and junior doctors would attend so I was very familiar with. One thing that was always done was an examination of the heart for arterial disease. In cases where a GP signed off...
  13. Jonathan Edwards

    Concerns about Cochrane

    I think we have probably established (elsewhere) that Chalmers and Gotzsche don't get it when it comes to CBT and GET for ME. Bastian might have a slightly wider-angled view I agree. But I suspect she will want to mend fences as well.
  14. Jonathan Edwards

    Concerns about Cochrane

    We need honesty and reality. Dismissed is the wrong word, but everyone should realise that in science: everyone can be considered as having a conflict, and no one should be trusted Ultimately Bastian, Chalmers and Gotzsche were all interfering do-gooders with a biased view. They may have done...
  15. Jonathan Edwards

    Berkeley Wellness: When Medical Symptoms Are Dismissed as "All in Your Head" (David Tuller interviews Maya Dusenbery)

    They were on the wards. There just wasn't so many of them. By and large women either got breast cancer or carried on until their sixties of seventies and had strokes. Maybe older people with coronaries were more likely to die before getting to hospital so the older women (and men) were...
  16. Jonathan Edwards

    Berkeley Wellness: When Medical Symptoms Are Dismissed as "All in Your Head" (David Tuller interviews Maya Dusenbery)

    David, be reasonable. I was the medical admitting doctor for the whole of the hospital one day a week. I admitted whoever came to the emergency room with chest pain. They all had the same diagnostic procedures. There were about four male coronaries for each female. If you think about it, if...
  17. Jonathan Edwards

    Berkeley Wellness: When Medical Symptoms Are Dismissed as "All in Your Head" (David Tuller interviews Maya Dusenbery)

    The article is clearly designed to make a gender point so I am not sure whether that statement is more than just a statement of the obvious. When I was an intern I had a male ward where half the patients were coronaries. In the female ward it was about a fifth or less. Moreover, the men with...
  18. Jonathan Edwards

    Berkeley Wellness: When Medical Symptoms Are Dismissed as "All in Your Head" (David Tuller interviews Maya Dusenbery)

    It wouldn't be a matter of how many. It would be a matter of whether it was necessary to subject women to experiments when men could be used and women who might be pregnant were considered best not subjected to experiment. Clearly a study of uterine cancer would require women but presumably men...
  19. Jonathan Edwards

    Berkeley Wellness: When Medical Symptoms Are Dismissed as "All in Your Head" (David Tuller interviews Maya Dusenbery)

    I am not sure what the first comment is about.We are talking about whether or not research was applied equally to mea and women. The vast majority of experiments designed to study disease would apply equally to men and women. New antimicrobials would affect them equally one would think, trials...
  20. Jonathan Edwards

    Berkeley Wellness: When Medical Symptoms Are Dismissed as "All in Your Head" (David Tuller interviews Maya Dusenbery)

    That quotes half a dozen odd studies. I cannot see a reason to think they are representative. The text is obviously trying to make a point. If it were really true that women were never studied it would surely not be a question of finding half a dozen studies.
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