The real story about these tweets to Sharpe is that he sought debate with sick and easily stressed patients and behaved rudely and dismissively. He did this for several months and in that timeframe got hundreds of responses which included some angry ones. That he now uses as evidence that...
Wessely was PACE trial centre leader and is acknowledged as having contributed to the trial design. I cannot imagine that the PACE authors would not have taken the opportunity to present evidence of death threats to the tribunal (even if the threats were only against someone that played a minor...
I think it's perfectly possible that such a video was produced and planted there by the BPS people. They have fabricated evidence before (see Crawley's claim of having received a threatening letter). PACE showed how dishonest they are. It's difficult to explain why such a video, if it was...
It would achieve what the BPS people want: that the press talks about anything other than BPS science being a fraud. I'm sure they don't mind articles about academics trading insults and accusations.
Ignore it where possible, it's just a distraction. Keep writing!
They love this kind of controversy, not the other kind about outcome switching and failure to control for placebo effects. So keep writing about the latter.
PS: you're going to have to write some response to the accusations, but...
Sure we can. If there's no money to be made from MUS diagnoses then they will stop inventing these diagnoses. That can be achieved by demanding that clinics must not offer treatments that haven't passed a well designed RCT.
Maybe we feel worse not because of the accumulation or depletion of molecule or signal X, but because the body senses that now it really needs to rest so that it can take care of this imbalance, and it can achieve prolonged rest by making us feel like crap.
A bit like most symptoms during a...
I also see this pattern of feeling not so bad or even OK while exerting, but being hit with exhaustion as soon as the body shifts into a resting state.
I'm also seeing the pattern of waking up and feeling awful because the day before I did too much. But during the day I probably felt good...
If I were to make a simulation of ME/CFs and PEM, then it would work a bit like this:
Engaging in activities generates exertion points proportional to the intensity and duration of exertion.
Sleep and rest removes exertion points proportional to the quality of the rest and sleep and duration...
Relevant to GET and measurement of activity patterns:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1280928/
In the original study, activity as measured by accelerometer increased, but symptoms worsened.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC555551/
Sounds as if it's still not clear if exercise protects or if there is some process that causes low physical activity levels and also increases risk of depression.
I just realized that the PACE authors are now probably living in fear of real consequences, because we're very close to the UK government waking up and realizing that it has been manipulated and lied to by dishonest researchers.
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